ID   PDAD1_ARCFU             Reviewed;         157 AA.
AC   O27983;
DT   11-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2002, sequence version 2.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Pyruvoyl-dependent arginine decarboxylase 1;
DE            Short=PvlArgDC 1;
DE            EC=4.1.1.19;
DE   Contains:
DE     RecName: Full=Pyruvoyl-dependent arginine decarboxylase 1 subunit beta;
DE   Contains:
DE     RecName: Full=Pyruvoyl-dependent arginine decarboxylase 1 subunit alpha;
GN   Name=pdaD1; OrderedLocusNames=AF_2301;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + L-arginine = agmatine + CO2; Xref=Rhea:RHEA:17641,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:32682,
CC         ChEBI:CHEBI:58145; EC=4.1.1.19;
CC   -!- COFACTOR:
CC       Name=pyruvate; Xref=ChEBI:CHEBI:15361; Evidence={ECO:0000250};
CC       Note=Binds 1 pyruvoyl group covalently per subunit. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the PdaD family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB88952.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000782; AAB88952.1; ALT_INIT; Genomic_DNA.
DR   PIR; E69537; E69537.
DR   AlphaFoldDB; O27983; -.
DR   SMR; O27983; -.
DR   STRING; 224325.AF_2301; -.
DR   EnsemblBacteria; AAB88952; AAB88952; AF_2301.
DR   KEGG; afu:AF_2301; -.
DR   eggNOG; arCOG04490; Archaea.
DR   HOGENOM; CLU_114389_0_0_2; -.
DR   OMA; VFCVMSR; -.
DR   PhylomeDB; O27983; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0008792; F:arginine decarboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006527; P:arginine catabolic process; IEA:InterPro.
DR   Gene3D; 3.50.20.10; -; 1.
DR   HAMAP; MF_01404; PvlArgDC; 1.
DR   InterPro; IPR016104; Pyr-dep_his/arg-deCO2ase.
DR   InterPro; IPR016105; Pyr-dep_his/arg-deCO2ase_sand.
DR   InterPro; IPR002724; Pyruvoyl-dep_arg_deCO2ase.
DR   PANTHER; PTHR40438; PTHR40438; 1.
DR   Pfam; PF01862; PvlArgDC; 1.
DR   PIRSF; PIRSF005216; Pyruvoyl-dep_arg_deCO2ase; 1.
DR   SFLD; SFLDG01170; Pyruvoyl-dependent_arginine_de; 1.
DR   SUPFAM; SSF56271; SSF56271; 1.
DR   TIGRFAMs; TIGR00286; TIGR00286; 1.
PE   3: Inferred from homology;
KW   Decarboxylase; Lyase; Pyruvate; Reference proteome.
FT   CHAIN           1..40
FT                   /note="Pyruvoyl-dependent arginine decarboxylase 1 subunit
FT                   beta"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000023304"
FT   CHAIN           41..157
FT                   /note="Pyruvoyl-dependent arginine decarboxylase 1 subunit
FT                   alpha"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000023305"
FT   SITE            40..41
FT                   /note="Cleavage (non-hydrolytic)"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         41
FT                   /note="Pyruvic acid (Ser)"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   157 AA;  17205 MW;  2A77CE5332244078 CRC64;
     MLPRKVFFTK GVGRHTDPLV SFELALRDAG IEKFNLVTVS SIYPPYCEIV EAEKGLSELF
     PGQIVFCVMS RMTSNEQGKR IFASVGAAIP PDPSLNGYLT EYHGYCNGED AGRHAEESAA
     YMLKTAFEIE PARTFNITVE ADVEDCTTVV AAAVFVI