ID   PDC2_CANAX              Reviewed;         836 AA.
AC   O60035;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Protein PDC2;
GN   Name=PDC2;
OS   Candida albicans (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5476;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10341421;
RX   DOI=10.1002/(sici)1097-0061(199905)15:7<585::aid-yea401>3.0.co;2-9;
RA   Kaiser B., Munder T., Saluz H.P., Kuenkel W., Eck R.;
RT   "Identification of a gene encoding the pyruvate decarboxylase gene
RT   regulator CaPdc2p from Candida albicans.";
RL   Yeast 15:585-591(1999).
CC   -!- FUNCTION: Essential for the synthesis of pyruvate decarboxylase.
CC       {ECO:0000250}.
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DR   EMBL; Y17007; CAA76580.1; -; Genomic_DNA.
DR   AlphaFoldDB; O60035; -.
DR   PRIDE; O60035; -.
DR   CGD; CAL0000185877; PDC2.
DR   VEuPathDB; FungiDB:C1_09970C_A; -.
DR   VEuPathDB; FungiDB:CAWG_00435; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR   Pfam; PF03184; DDE_1; 1.
DR   Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR   SMART; SM00674; CENPB; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS51253; HTH_CENPB; 1.
PE   3: Inferred from homology;
KW   DNA-binding.
FT   CHAIN           1..836
FT                   /note="Protein PDC2"
FT                   /id="PRO_0000126136"
FT   DOMAIN          64..139
FT                   /note="HTH CENPB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00583"
FT   REGION          626..732
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        626..652
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        669..732
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   836 AA;  94360 MW;  E4030FC8D5C694C7 CRC64;
     MGYTIKQKIG ICLKAEANPE MTQSDLALWA MKEYNSERPP SQTTISRILN SKNDIISRKE
     SEFELIRRRK RANPLLRRIL TEWITQANWE GIPITTPIIQ STANAIWTRL PKEGQEGNGI
     FNQKWCSHFV KKLNINITGS PRDVLDNRGY NLNKVWKLDE ILELKRYLRD IIDQEDYAPQ
     DVFVIDDFQL FYSLPLDQIF DVSSIDKGIK QSNSSAEHSL TIMLGCNIDG SEKLTPIIVG
     KYDKFDVSKS THVSLNSMQF DSVSYQTLMN KLTEVYNIFY KSNTNKWITS SMFQNYLTRL
     DHKLSNSRPN GRKILIILDD CSSHRIINLK FNNIRLCYLK NEANHKNPYN TTYSGIKFDY
     LPMNFGIVEE FKILYRLQQY LEMINLQRSK SQIDSDPMIE ENLTSTSVAT TATALEVLSE
     SDYHISLIRA IEWITRSWHS VSSERIFSSW KKTHLFNLLD WPSGNSGQLV YLNQKLNTFD
     ENKSLKKLKE VMSYLNVVIP WEIDELVGLV NERGKVTLSY ASIEEIIDSC LSEPVDDYDE
     MGDDDGRFDN RKNELGDVSS VPVDNSNDPW FTVSEINEFH NDPFYNNDKS IDAAAEPLES
     ISPDNDSSAI PGLETKALSA ISGLGTTSTS VVSDSPSGTT QKYNNISTYP NGSLKHKLGV
     LENWNRKRGP GQGQGQGQEL QNPQGQQQQE QQQQQQHQMS GYNFSPISNI ESPIASGGLT
     NPNVQFGNGA GSFDNQTPLF MNSLTSPPPP PPVPVPVPVP VPSVPSQVPA TSFPQDVSSS
     RAVRAPMSTA AVDVDMATAI TKLLEYSASN TLKLSQSTID DLDYNLRVIR ARLNQR