PDCD5_BOVIN
ID PDCD5_BOVIN Reviewed; 125 AA.
AC Q2HJH9;
DT 11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Programmed cell death protein 5;
GN Name=PDCD5;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May function in the process of apoptosis. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PDCD5 family. {ECO:0000305}.
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DR EMBL; BC105370; AAI05371.1; -; mRNA.
DR RefSeq; NP_001039489.1; NM_001046024.1.
DR AlphaFoldDB; Q2HJH9; -.
DR SMR; Q2HJH9; -.
DR STRING; 9913.ENSBTAP00000012256; -.
DR PaxDb; Q2HJH9; -.
DR PRIDE; Q2HJH9; -.
DR Ensembl; ENSBTAT00000012256; ENSBTAP00000012256; ENSBTAG00000009304.
DR GeneID; 509123; -.
DR KEGG; bta:509123; -.
DR CTD; 9141; -.
DR VEuPathDB; HostDB:ENSBTAG00000009304; -.
DR VGNC; VGNC:32662; PDCD5.
DR eggNOG; KOG3431; Eukaryota.
DR GeneTree; ENSGT00390000011085; -.
DR HOGENOM; CLU_122978_4_0_1; -.
DR InParanoid; Q2HJH9; -.
DR OMA; KPQFGEQ; -.
DR OrthoDB; 1645187at2759; -.
DR TreeFam; TF313112; -.
DR Proteomes; UP000009136; Chromosome 18.
DR Bgee; ENSBTAG00000009304; Expressed in oocyte and 103 other tissues.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0010698; F:acetyltransferase activator activity; IEA:Ensembl.
DR GO; GO:0048487; F:beta-tubulin binding; IEA:Ensembl.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:1903645; P:negative regulation of chaperone-mediated protein folding; IEA:Ensembl.
DR GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR GO; GO:1903638; P:positive regulation of protein insertion into mitochondrial outer membrane; IEA:Ensembl.
DR GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IEA:Ensembl.
DR Gene3D; 1.10.8.140; -; 1.
DR InterPro; IPR002836; PDCD5-like.
DR InterPro; IPR036883; PDCD5-like_sf.
DR PANTHER; PTHR10840; PTHR10840; 1.
DR Pfam; PF01984; dsDNA_bind; 1.
DR PIRSF; PIRSF015730; TFAR19; 1.
DR SUPFAM; SSF46950; SSF46950; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Apoptosis; Phosphoprotein; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:O14737"
FT CHAIN 2..125
FT /note="Programmed cell death protein 5"
FT /id="PRO_0000245574"
FT REGION 17..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0000250|UniProtKB:O14737"
FT MOD_RES 51
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:O14737"
FT MOD_RES 63
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:O14737"
FT MOD_RES 119
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:O14737"
SQ SEQUENCE 125 AA; 14226 MW; DF72A071D4609AC2 CRC64;
MAEQELEALR KQRLAELQAK HGDPGDAAQQ EAKHREAEMR NSILAQVLDQ SARARLSNLA
LVKPEKTKAV ENYLIQMARY GQLSGKVSEQ GLIEILEKVS QQTEKKTTVK FNRRKVMDSD
EDDDY
