ID   PDCT2_ARATH             Reviewed;         296 AA.
AC   Q9LVZ6;
DT   22-JAN-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Phosphatidylcholine:diacylglycerol cholinephosphotransferase 2;
DE            Short=AtPDCT2;
DE            EC=2.7.8.-;
GN   OrderedLocusNames=At3g15830; ORFNames=MSJ11.23;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions as phosphatidylcholine:diacylglycerol
CC       cholinephosphotransferase that catalyzes the transfer of the
CC       phosphocholine headgroup from phosphatidylcholine (PC) to
CC       diacylglycerol, a major reaction for the transfer of 18:1 into
CC       phosphatidylcholine for desaturation and also for the reverse transfer
CC       of 18:2 and 18:3 into the triacylglycerols synthesis pathway.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the phosphatidylcholine:diacylglycerol
CC       cholinephosphotransferase family. {ECO:0000305}.
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DR   EMBL; AB017071; BAB02314.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE75731.1; -; Genomic_DNA.
DR   EMBL; DR288877; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; DR378318; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_188204.1; NM_112453.3.
DR   AlphaFoldDB; Q9LVZ6; -.
DR   STRING; 3702.AT3G15830.1; -.
DR   PaxDb; Q9LVZ6; -.
DR   PRIDE; Q9LVZ6; -.
DR   EnsemblPlants; AT3G15830.1; AT3G15830.1; AT3G15830.
DR   GeneID; 820826; -.
DR   Gramene; AT3G15830.1; AT3G15830.1; AT3G15830.
DR   KEGG; ath:AT3G15830; -.
DR   Araport; AT3G15830; -.
DR   TAIR; locus:2093272; AT3G15830.
DR   eggNOG; ENOG502QRYQ; Eukaryota.
DR   HOGENOM; CLU_079484_0_0_1; -.
DR   InParanoid; Q9LVZ6; -.
DR   OMA; QMVYIVW; -.
DR   OrthoDB; 895973at2759; -.
DR   PhylomeDB; Q9LVZ6; -.
DR   PRO; PR:Q9LVZ6; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LVZ6; baseline and differential.
DR   Genevisible; Q9LVZ6; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004142; F:diacylglycerol cholinephosphotransferase activity; ISS:UniProtKB.
DR   GO; GO:0046470; P:phosphatidylcholine metabolic process; ISS:UniProtKB.
PE   2: Evidence at transcript level;
KW   Lipid metabolism; Membrane; Reference proteome; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..296
FT                   /note="Phosphatidylcholine:diacylglycerol
FT                   cholinephosphotransferase 2"
FT                   /id="PRO_0000425111"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        211
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        251
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        255
FT                   /evidence="ECO:0000250"
FT   CONFLICT        125
FT                   /note="S -> N (in Ref. 3; DR288877/DR378318)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        233
FT                   /note="V -> F (in Ref. 3; DR378318)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        274
FT                   /note="E -> K (in Ref. 3; DR378318)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   296 AA;  32691 MW;  B5BCD83423353EFE CRC64;
     MSDAVTKTVA PLRRKANPIN GKHTNGVTID GIFDDHNRQI GPINSQMEDI AQKTDDGGGG
     EWTSKASFMT WTMHDIIYVA RHHWIPCLFA AGVMFFTVVE YTFQMTPASS QPFDLGFVAT
     RYLHSILASS PNLNTVLAAL NTILVGMQTT YIGCTWAVEG RPRATIAALF MFTCRGILGY
     STQLPRPQEF LGSGVDYPVG NVSFFLFYSG HVAGSMIASL DMKRMQRFRL AMVFDILNVL
     QSIRLLGTRG HYTIDIAVGV GAGILFDSLA GKYEEMSKRH LRNTRCSLIS KDSLVT