ID   PDE6D_DROPS             Reviewed;         151 AA.
AC   Q29JT7;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta;
GN   Name=PrBP {ECO:0000250|UniProtKB:Q9VLJ0}; ORFNames=GA21678;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1] {ECO:0000312|EMBL:EAL32874.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- SUBUNIT: Interacts with Pde6. {ECO:0000250|UniProtKB:Q9VLJ0}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9VLJ0}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q9VLJ0}.
CC   -!- SIMILARITY: Belongs to the PDE6D/unc-119 family. {ECO:0000255}.
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DR   EMBL; CH379062; EAL32874.1; -; Genomic_DNA.
DR   RefSeq; XP_001355815.1; XM_001355779.3.
DR   AlphaFoldDB; Q29JT7; -.
DR   SMR; Q29JT7; -.
DR   STRING; 7237.FBpp0285788; -.
DR   EnsemblMetazoa; FBtr0368600; FBpp0331333; FBgn0081663.
DR   GeneID; 4816170; -.
DR   KEGG; dpo:Dpse_GA21678; -.
DR   eggNOG; KOG4038; Eukaryota.
DR   HOGENOM; CLU_119682_0_0_1; -.
DR   InParanoid; Q29JT7; -.
DR   OMA; FKGRCLE; -.
DR   PhylomeDB; Q29JT7; -.
DR   Proteomes; UP000001819; Chromosome 4.
DR   Bgee; FBgn0081663; Expressed in male reproductive system and 2 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0016319; P:mushroom body development; IEA:EnsemblMetazoa.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IEA:InterPro.
DR   Gene3D; 2.70.50.40; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR008015; PDED_dom.
DR   InterPro; IPR037036; PDED_dom_sf.
DR   InterPro; IPR017287; Rhodop-sen_GMP-Pdiesterase_dsu.
DR   Pfam; PF05351; GMP_PDE_delta; 1.
DR   PIRSF; PIRSF037825; GMP-Pdiesterase_delta; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   cGMP; Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..151
FT                   /note="Probable cGMP 3',5'-cyclic phosphodiesterase subunit
FT                   delta"
FT                   /id="PRO_0000363678"
SQ   SEQUENCE   151 AA;  17320 MW;  0A3337CA52DC7593 CRC64;
     MGSDDQSAAD KIQKGFQINY MILRDADSGK IIWQENKDFS APDVEHEARV PVKILDMRAV
     SREINFSTVE SMENFRLDQK VLFKGRIMEE WFFEMGFVGA STTNTWQSTI EAAPESQMMP
     AKVLNGNVTI QTSFYDNETL ITKSVVRLYY I