ID   PDLI3_XENLA             Reviewed;         358 AA.
AC   Q6GLJ6;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=PDZ and LIM domain protein 3;
GN   Name=pdlim3;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the organization of actin filament arrays
CC       within muscle cells. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril, sarcomere, Z line
CC       {ECO:0000250}. Note=Localizes to myofiber Z-lines. {ECO:0000250}.
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DR   EMBL; BC074488; AAH74488.1; -; mRNA.
DR   RefSeq; NP_001086326.1; NM_001092857.1.
DR   AlphaFoldDB; Q6GLJ6; -.
DR   SMR; Q6GLJ6; -.
DR   DNASU; 444755; -.
DR   GeneID; 444755; -.
DR   KEGG; xla:444755; -.
DR   CTD; 444755; -.
DR   Xenbase; XB-GENE-6077880; pdlim3.L.
DR   OMA; IHAQFNT; -.
DR   OrthoDB; 840552at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 444755; Expressed in muscle tissue and 17 other tissues.
DR   GO; GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR031847; DUF4749.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR006643; Zasp-like_motif.
DR   InterPro; IPR001781; Znf_LIM.
DR   Pfam; PF15936; DUF4749; 1.
DR   Pfam; PF00412; LIM; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM00132; LIM; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SMART; SM00735; ZM; 1.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; LIM domain; Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..358
FT                   /note="PDZ and LIM domain protein 3"
FT                   /id="PRO_0000075872"
FT   DOMAIN          1..84
FT                   /note="PDZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   DOMAIN          288..347
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT   REGION          126..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          237..274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        130..155
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   358 AA;  38979 MW;  EEA078A7D80D989A CRC64;
     MPQNVLLPGP APWGFRLTGG IDFNQPLVIS RITPGSKSSV ANLCPGDVIL AIDGFSTETM
     THAEAQDRIK AATDQLCLKI DRAETRIWSP QVCEDGKAQP FKINLEAEPQ DLGFFEHKHN
     IRPKPFILPG RSSGSSTPSG FDPGSGRSTP SSVSTIDPVE LKAASRIAPN VPLEMELPGV
     KIVHAQFNTP MQLYSDDNIM ESLQGQVSTI LGEKTPMSDP VPPSVPQSDV YKLLHDDTEH
     PSKPRQSGSF KILQDMVDDD PDRPSGTRSV RAPVTKPNTG AAAVQKVPIC DRCGNGIVGT
     VVKAKDKLRH PDCFVCSDCN LNLKQKGYFF VEGQLYCEAH ARARMRPPEG YDAVTVYH