ID   PDLI7_XENLA             Reviewed;         421 AA.
AC   Q6INU3;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=PDZ and LIM domain protein 7;
GN   Name=pdlim7;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May function as a scaffold on which the coordinated assembly
CC       of proteins can occur. May play a role as an adapter that, via its PDZ
CC       domain, localizes LIM-binding proteins to actin filaments of both
CC       skeletal muscle and nonmuscle tissues (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- DOMAIN: The LIM zinc-binding 3 (LIM 3) domain provides the structural
CC       basis for recognition of tyrosine-containing tight turn structures.
CC       {ECO:0000250}.
CC   -!- DOMAIN: Anchored to cell periphery via its N-terminal PDZ domain.
CC       {ECO:0000250}.
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DR   EMBL; BC072179; AAH72179.1; -; mRNA.
DR   AlphaFoldDB; Q6INU3; -.
DR   SMR; Q6INU3; -.
DR   IntAct; Q6INU3; 1.
DR   OMA; ESQRICH; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR001781; Znf_LIM.
DR   Pfam; PF00412; LIM; 3.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM00132; LIM; 3.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 3.
DR   PROSITE; PS50106; PDZ; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoskeleton; LIM domain; Metal-binding; Reference proteome;
KW   Repeat; Zinc.
FT   CHAIN           1..421
FT                   /note="PDZ and LIM domain protein 7"
FT                   /id="PRO_0000075886"
FT   DOMAIN          1..85
FT                   /note="PDZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   DOMAIN          244..302
FT                   /note="LIM zinc-binding 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT   DOMAIN          303..362
FT                   /note="LIM zinc-binding 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT   DOMAIN          363..421
FT                   /note="LIM zinc-binding 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT   REGION          115..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        150..174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   421 AA;  46427 MW;  75EB7169099CBB27 CRC64;
     MEEYKVTLDG PAPWGFRLQG GKDFNMPLSI SRLTPGGKSE LAGVNVGDWL LQIEGDSTAS
     MTHIEAQNKI RASSNKLGLV LSRFAVGANH PKGVHTPESQ GRKYNFAPST ALNKIARPFG
     SGTPPPDNSR PVQVTKPVAY NPPPTSYPSS QMPQGQLQNG QKSRTVSNVS GKDTTDHPIP
     PAPSTGPAVR PPWTTDPTFA DRYAPDKTTT VMTKHTQPAT PTPAQSRNSI LQAAQVPSSG
     DKTPVCSQCN KIIRGRFLLA LGRYYHPEEF TCSQCHKVLE EGGFFEEKGS IFCPCCYDAR
     FAPNCAKCKK KITGEIMHAL KMTWHVPCFT CAYCKTPIRN RAFYMEDGKP YCEKDYEQMF
     GTKCRGCDFK IDAGDRFLEA LGFSWHDTCF VCAICQINLE GKTFYSKKDK PLCKTHAFSN
     V