PDRG1_BOVIN
ID PDRG1_BOVIN Reviewed; 133 AA.
AC Q148L7;
DT 17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=p53 and DNA damage-regulated protein 1;
GN Name=PDRG1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Thalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in chaperone-mediated protein folding.
CC {ECO:0000305}.
CC -!- SUBUNIT: Component of the PAQosome complex which is responsible for the
CC biogenesis of several protein complexes and which consists of R2TP
CC complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members
CC PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and
CC DNAAF10/WDR92. {ECO:0000250|UniProtKB:Q9NUG6}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC {ECO:0000305}.
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DR EMBL; BC118162; AAI18163.1; -; mRNA.
DR RefSeq; NP_001071583.1; NM_001078115.1.
DR AlphaFoldDB; Q148L7; -.
DR SMR; Q148L7; -.
DR STRING; 9913.ENSBTAP00000012845; -.
DR PaxDb; Q148L7; -.
DR Ensembl; ENSBTAT00000012845; ENSBTAP00000012845; ENSBTAG00000009743.
DR GeneID; 768241; -.
DR KEGG; bta:768241; -.
DR CTD; 81572; -.
DR VEuPathDB; HostDB:ENSBTAG00000009743; -.
DR VGNC; VGNC:32716; PDRG1.
DR eggNOG; ENOG502S6V9; Eukaryota.
DR GeneTree; ENSGT00390000013253; -.
DR HOGENOM; CLU_132161_0_0_1; -.
DR InParanoid; Q148L7; -.
DR OMA; RQKCREA; -.
DR OrthoDB; 1630799at2759; -.
DR TreeFam; TF329240; -.
DR Proteomes; UP000009136; Chromosome 13.
DR Bgee; ENSBTAG00000009743; Expressed in triceps brachii and 106 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016272; C:prefoldin complex; IEA:InterPro.
DR GO; GO:1990062; C:RPAP3/R2TP/prefoldin-like complex; IEA:Ensembl.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR Gene3D; 1.10.287.370; -; 1.
DR InterPro; IPR030482; PDRG1.
DR InterPro; IPR002777; PFD_beta-like.
DR InterPro; IPR009053; Prefoldin.
DR PANTHER; PTHR21162; PTHR21162; 1.
DR Pfam; PF01920; Prefoldin_2; 1.
PE 2: Evidence at transcript level;
KW Chaperone; Cytoplasm; Reference proteome.
FT CHAIN 1..133
FT /note="p53 and DNA damage-regulated protein 1"
FT /id="PRO_0000252489"
SQ SEQUENCE 133 AA; 15610 MW; A4A424D20154111F CRC64;
MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNRN REGLRALQKD LSLTEDVMVC
FGNMFIRMPH PETKEMIEKD QEHLDKEIER LRKQLKVKVN RLFEAQGKPE LKGFNLTPLN
QDELKALKVI LKG