ID   PDRG1_RAT               Reviewed;         133 AA.
AC   Q642A0;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 2.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=p53 and DNA damage-regulated protein 1;
GN   Name=Pdrg1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May play a role in chaperone-mediated protein folding.
CC       {ECO:0000305}.
CC   -!- SUBUNIT: Component of the PAQosome complex which is responsible for the
CC       biogenesis of several protein complexes and which consists of R2TP
CC       complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members
CC       PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and
CC       DNAAF10/WDR92. {ECO:0000250|UniProtKB:Q9NUG6}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC       {ECO:0000305}.
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DR   EMBL; BC082021; AAH82021.2; -; mRNA.
DR   RefSeq; NP_001014762.1; NM_001014762.1.
DR   AlphaFoldDB; Q642A0; -.
DR   SMR; Q642A0; -.
DR   BioGRID; 255302; 3.
DR   STRING; 10116.ENSRNOP00000012142; -.
DR   PaxDb; Q642A0; -.
DR   GeneID; 296278; -.
DR   KEGG; rno:296278; -.
DR   UCSC; RGD:1305096; rat.
DR   CTD; 81572; -.
DR   RGD; 1305096; Pdrg1.
DR   eggNOG; ENOG502S6V9; Eukaryota.
DR   HOGENOM; CLU_132161_0_0_1; -.
DR   InParanoid; Q642A0; -.
DR   OMA; RQKCREA; -.
DR   OrthoDB; 1630799at2759; -.
DR   PhylomeDB; Q642A0; -.
DR   TreeFam; TF329240; -.
DR   PRO; PR:Q642A0; -.
DR   Proteomes; UP000002494; Chromosome 3.
DR   Bgee; ENSRNOG00000008845; Expressed in skeletal muscle tissue and 20 other tissues.
DR   Genevisible; Q642A0; RN.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:1990062; C:RPAP3/R2TP/prefoldin-like complex; ISO:RGD.
DR   InterPro; IPR030482; PDRG1.
DR   PANTHER; PTHR21162; PTHR21162; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Cytoplasm; Reference proteome.
FT   CHAIN           1..133
FT                   /note="p53 and DNA damage-regulated protein 1"
FT                   /id="PRO_0000252491"
SQ   SEQUENCE   133 AA;  15392 MW;  1185AC7047EE443F CRC64;
     MVSPEADRVL RYLVEVEELA EAVLSDKRQI VDLDTKRNQN REGLRALQKD PSVSEDVMVC
     FGNMFIKMPH LKTKEMIQKD QEHLDKEIER LRSQLKVKVN RLLEAQGKPE LKGFNLNPLN
     QDELKALQVI LKG