ID   ASR2_YERPE              Reviewed;         121 AA.
AC   Q8ZDC4; Q0WDN4;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Acid shock protein 2;
DE   Flags: Precursor;
GN   Name=asr2; Synonyms=asr; OrderedLocusNames=YPO2652, y1226, YP_2454;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: Required for growth and/or survival at acidic conditions.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- PTM: Proteolytic processing gives rise to the active protein.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Asr family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAM84801.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAS62655.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL590842; CAL21273.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM84801.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE017042; AAS62655.1; ALT_INIT; Genomic_DNA.
DR   PIR; AF0323; AF0323.
DR   RefSeq; WP_002212215.1; NZ_WUCM01000006.1.
DR   RefSeq; YP_002347604.1; NC_003143.1.
DR   AlphaFoldDB; Q8ZDC4; -.
DR   STRING; 214092.YPO2652; -.
DR   PaxDb; Q8ZDC4; -.
DR   EnsemblBacteria; AAM84801; AAM84801; y1226.
DR   GeneID; 57976040; -.
DR   KEGG; ype:YPO2652; -.
DR   KEGG; ypk:y1226; -.
DR   PATRIC; fig|214092.21.peg.3085; -.
DR   eggNOG; ENOG5032U9T; Bacteria.
DR   HOGENOM; CLU_102486_1_0_6; -.
DR   OMA; KVHHKKA; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0010447; P:response to acidic pH; IEA:InterPro.
DR   HAMAP; MF_00546; Asr; 1.
DR   InterPro; IPR023497; Acid_shock.
DR   InterPro; IPR009435; Asr.
DR   Pfam; PF06392; Asr; 1.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000250"
FT   PROPEP          22..63
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000269511"
FT   CHAIN           64..121
FT                   /note="Acid shock protein 2"
FT                   /id="PRO_0000002411"
FT   REGION          40..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..75
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   121 AA;  12580 MW;  274939C1BA36F864 CRC64;
     MKKVLALMVA ATLGLSSVAF AADTTATATP AATSTTATVA AQTKATQHQK HKVTKKTTEQ
     KAQAAKKHEK KASVQKTPVQ KAQAAKKHVK KASVQKAPVQ KAQAAKKHHK TAKKPVAAPA
     A