ID   PDS5A_CHICK             Reviewed;        1330 AA.
AC   Q5F3V3;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Sister chromatid cohesion protein PDS5 homolog A;
GN   Name=PDS5A {ECO:0000250|UniProtKB:Q29RF7}; ORFNames=RCJMB04_6f4;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1] {ECO:0000312|EMBL:CAH65181.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB {ECO:0000312|EMBL:CAH65181.1};
RC   TISSUE=Bursa of Fabricius {ECO:0000312|EMBL:CAH65181.1};
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May regulate sister chromatid cohesion during mitosis and
CC       couple it to DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the cohesin complex. Binds chromatin in a
CC       cohesin-dependent manner (By similarity).
CC       {ECO:0000250|UniProtKB:Q29RF7}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q29RF7}.
CC   -!- SIMILARITY: Belongs to the PDS5 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAH65181.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AJ851547; CAH65181.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001012598.1; NM_001012580.1.
DR   AlphaFoldDB; Q5F3V3; -.
DR   SMR; Q5F3V3; -.
DR   STRING; 9031.ENSGALP00000023059; -.
DR   PaxDb; Q5F3V3; -.
DR   GeneID; 422787; -.
DR   KEGG; gga:422787; -.
DR   CTD; 23244; -.
DR   VEuPathDB; HostDB:geneid_422787; -.
DR   eggNOG; KOG1525; Eukaryota.
DR   InParanoid; Q5F3V3; -.
DR   OrthoDB; 69768at2759; -.
DR   PhylomeDB; Q5F3V3; -.
DR   PRO; PR:Q5F3V3; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR   GO; GO:0007064; P:mitotic sister chromatid cohesion; IBA:GO_Central.
DR   GO; GO:0008156; P:negative regulation of DNA replication; ISS:UniProtKB.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039776; Pds5.
DR   PANTHER; PTHR12663; PTHR12663; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Mitosis; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..1330
FT                   /note="Sister chromatid cohesion protein PDS5 homolog A"
FT                   /id="PRO_0000296344"
FT   REPEAT          387..423
FT                   /note="HEAT"
FT                   /evidence="ECO:0000255"
FT   REGION          1138..1330
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1149..1196
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1213..1243
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1330 AA;  150132 MW;  0241C02AEF8C1AF4 CRC64;
     MDFPAAQPKP AADGKIIYYP PGVKETTDKI TNDEVVKRLK MVVKTFMDMD QDSEDEKQQY
     LPLALHLASE FFLRNPNKDV RLLVACCLAD IFRIYAPEAP YTSHDKLKDI FLFITRQLKG
     LEDTKSPQFN RYFYLLENLA WVKSYNICFE LEDCNEIFIQ LFRTLFSVIN NSHNQKVQMH
     MLDLMSSIIM EGDGVTQELL DSILINLIPA HKNLNKQAFD LAKVLLKRTV QTIEPCIANF
     FNQVLVLGKS SVSDLSEHVF DLILELFAID PHLLLSVMPQ LEFKLKSNDG EERLAVVRLL
     AKLFGSKDSD LATQNRPLWQ CFLGRFNDIH VPVRLESVKF ASHCLMNHPD LAKDLTEYLK
     VRSHDPEEAI RHDVIVTIIT AGKRDLSLVN DQLLGFVRER TLDKRWRVRK EAMMGLAQLY
     KKYCLHAEAG KDAAEKVSWI KDKLLHIYYQ NSIDDKLLVE KIFAQYLVPH NLETEERMKC
     LYYLYASLDP NAVKALNEMW KCQNMLRSHV RELLDLHKQP TSEANSAAMF GKLMTIAKNL
     PDPGKAQDFV KKFNQVLGDD EKLRSQLELL ISPTCSCKQA DVCVREIARK LANPKQPTNP
     FLEMVKFLLE RIAPVHIDSE AISALVKLMN KSIEGTADDE EEGVSPDTAI RAGLELLKVL
     SFTHPTSFHS AETYESLLQC LRMEDDKVAE AAIQIFRNTG HKIETDLPQI RSTLIPILHQ
     KAKRGTPHQA KQAVHCIHAI FSNKEVQLAQ IFEPLSRSLN ADVPEQLITP LVSLGHISML
     APDQFASPMK SVVANFVVKD LLMNDRSTGE KNGKLWSPDE EVSPEVLAKV QAIKLLVRWL
     LGMKNNQSKS ANSTLRLLSA MLVSEGDLTE QKRISKSDMS RLRLAAGSAI MKLAQEPCYH
     EIITPEQFQL CALVINDECY QVRQIFAQKL HKALVKLLLP LEYMAIFALC AKDPVKERRA
     HARQCLLKNI SIRREYIKQN PMANEKLLSL LPEYVVPYMI HLLAHDPDFT KPQDVDQLRD
     VKECLWFMLE VLMTKNENNS HAFMKKMAEN IKLTRDAQSP DEPKANEKLY TVCDVALCVI
     NSKSALCNAD SPKDPVLPTK FFTQPEKDFS NDRNYISEET RVLLLTGKPK PTGVLDTVNK
     PLSATGRRPY IRTTGSETGS NISVNSELSS SAGNRSREQS SDISETGVSE NDENPVRIIS
     VTPAKTEPVK NKEINSDQAT QGNSTERGKK RTATASGTEN IHQKAEENNA DETGPSLAAK
     TRRGRPPKPE PQGTTAKNEE TNKPPVRGRK RAAASQESPG SLEAGNAKAP KQQDTAKKPA
     AAQRQIDLQR