ID   ASR_ECO57               Reviewed;         102 AA.
AC   Q8X783;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Acid shock protein;
DE   Flags: Precursor;
GN   Name=asr; OrderedLocusNames=Z2591, ECs2303;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Required for growth and/or survival at acidic conditions.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- PTM: Proteolytic processing gives rise to the active protein.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Asr family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG56584.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAB35726.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE005174; AAG56584.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB35726.1; ALT_INIT; Genomic_DNA.
DR   PIR; D85765; D85765.
DR   PIR; G90916; G90916.
DR   RefSeq; NP_310330.2; NC_002695.1.
DR   RefSeq; WP_001414237.1; NZ_SWKA01000004.1.
DR   AlphaFoldDB; Q8X783; -.
DR   STRING; 155864.EDL933_2548; -.
DR   EnsemblBacteria; AAG56584; AAG56584; Z2591.
DR   EnsemblBacteria; BAB35726; BAB35726; ECs_2303.
DR   GeneID; 912800; -.
DR   KEGG; ece:Z2591; -.
DR   KEGG; ecs:ECs_2303; -.
DR   PATRIC; fig|386585.9.peg.2412; -.
DR   eggNOG; ENOG5032U9T; Bacteria.
DR   HOGENOM; CLU_102486_2_0_6; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_00546; Asr; 1.
DR   InterPro; IPR023497; Acid_shock.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000250"
FT   PROPEP          22..58
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000269505"
FT   CHAIN           59..102
FT                   /note="Acid shock protein"
FT                   /id="PRO_0000002404"
FT   REGION          22..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..67
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   102 AA;  10561 MW;  25881B586D2964AE CRC64;
     MKKVLALVVA AAMGLSSAAF AAETATTPAP TATTTKAAPA KTTHHKKQHK AAPAQKAQAA
     KKHHKNTKAE QKAPEQKAQA AKKHAKKHSH QQPAKPAAQP AA