ID   PDTAR_MYCTO             Reviewed;         205 AA.
AC   P9WGM2; L0T8T8; O06143; Q7D890;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Probable transcriptional regulatory protein PdtaR;
GN   Name=pdtaR; OrderedLocusNames=MT1662;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Member of the two-component regulatory system PdtaR/PdtaS.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. Dimer; when bound to its cognate DNA (Potential).
CC       {ECO:0000305}.
CC   -!- PTM: Phosphorylated by PdtaS. {ECO:0000250}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK45932.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE000516; AAK45932.1; ALT_INIT; Genomic_DNA.
DR   PIR; H70558; H70558.
DR   RefSeq; WP_003408045.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WGM2; -.
DR   SMR; P9WGM2; -.
DR   EnsemblBacteria; AAK45932; AAK45932; MT1662.
DR   GeneID; 45425595; -.
DR   KEGG; mtc:MT1662; -.
DR   PATRIC; fig|83331.31.peg.1785; -.
DR   HOGENOM; CLU_000445_65_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005561; ANTAR.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR008327; Sig_transdc_resp-reg_antiterm.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF03861; ANTAR; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PIRSF; PIRSF036382; RR_antiterm; 1.
DR   SMART; SM01012; ANTAR; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50921; ANTAR; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Transcription; Transcription antitermination;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..205
FT                   /note="Probable transcriptional regulatory protein PdtaR"
FT                   /id="PRO_0000428337"
FT   DOMAIN          15..129
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          135..196
FT                   /note="ANTAR"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00308"
FT   MOD_RES         65
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   205 AA;  22669 MW;  C57AD16BAD0E3C0B CRC64;
     MTGPTTDADA AVPRRVLIAE DEALIRMDLA EMLREEGYEI VGEAGDGQEA VELAELHKPD
     LVIMDVKMPR RDGIDAASEI ASKRIAPIVV LTAFSQRDLV ERARDAGAMA YLVKPFSISD
     LIPAIELAVS RFREITALEG EVATLSERLE TRKLVERAKG LLQTKHGMTE PDAFKWIQRA
     AMDRRTTMKR VAEVVLETLG TPKDT