ID   PDUA_SALTI              Reviewed;          94 AA.
AC   P0A1C8; P37448;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Bacterial microcompartment shell protein PduA;
DE   AltName: Full=Bacterial microcompartment protein homohexamer {ECO:0000305};
DE            Short=BMC-H;
DE   AltName: Full=Propanediol utilization protein PduA;
GN   Name=pduA; OrderedLocusNames=STY2243, t0836;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: One of the major shell proteins of the bacterial
CC       microcompartment (BMC) dedicated to 1,2-propanediol (1,2-PD)
CC       degradation. At least one of PduA or PduJ is required for BMC assembly.
CC       Controls diffusion of 1,2-PD into and propionaldehyde out of the BMC
CC       shell. PduA is probably the hub for binding multiple enzymes to the
CC       interior of the BMC. {ECO:0000250|UniProtKB:P0A1C7}.
CC   -!- FUNCTION: The 1,2-PD-specific bacterial microcompartment (BMC)
CC       concentrates low levels of 1,2-PD catabolic enzymes, concentrates
CC       volatile reaction intermediates thus enhancing pathway flux and keeps
CC       the level of toxic, mutagenic propionaldehyde low.
CC       {ECO:0000250|UniProtKB:P0A1C7}.
CC   -!- PATHWAY: Polyol metabolism; 1,2-propanediol degradation.
CC       {ECO:0000250|UniProtKB:P0A1C7}.
CC   -!- SUBUNIT: Homohexamer with a central pore of about 5.6 Angstroms in
CC       diameter. The hexamers pack against each other in arrays. Interacts
CC       with the N-terminus of PduP which targets PduP to the BMC, probably
CC       interacts with other subunits as well. {ECO:0000250|UniProtKB:P0A1C7}.
CC   -!- SUBCELLULAR LOCATION: Bacterial microcompartment
CC       {ECO:0000250|UniProtKB:P0A1C7}. Note=The concave face and both termini
CC       probably face the interior of the BMC. {ECO:0000250|UniProtKB:P0A1C7}.
CC   -!- INDUCTION: By propanediol. {ECO:0000250|UniProtKB:P0A1C7}.
CC   -!- SIMILARITY: Belongs to the bacterial microcompartments protein family.
CC       {ECO:0000255|PROSITE-ProRule:PRU01278}.
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DR   EMBL; AL513382; CAD02399.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO68524.1; -; Genomic_DNA.
DR   RefSeq; NP_456588.1; NC_003198.1.
DR   RefSeq; WP_001183618.1; NZ_WSUR01000002.1.
DR   AlphaFoldDB; P0A1C8; -.
DR   SMR; P0A1C8; -.
DR   STRING; 220341.16503269; -.
DR   EnsemblBacteria; AAO68524; AAO68524; t0836.
DR   GeneID; 64335893; -.
DR   GeneID; 66587154; -.
DR   KEGG; stt:t0836; -.
DR   KEGG; sty:STY2243; -.
DR   PATRIC; fig|220341.7.peg.2262; -.
DR   eggNOG; COG4577; Bacteria.
DR   HOGENOM; CLU_064903_5_3_6; -.
DR   OMA; HSEVEMI; -.
DR   UniPathway; UPA00621; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0031469; C:bacterial microcompartment; IEA:UniProtKB-SubCell.
DR   GO; GO:0051144; P:propanediol catabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.30.70.1710; -; 1.
DR   InterPro; IPR020808; Bact_microcomp_CS.
DR   InterPro; IPR000249; BMC_dom.
DR   InterPro; IPR037233; CcmK-like_sf.
DR   InterPro; IPR044872; CcmK/CsoS1_BMC.
DR   Pfam; PF00936; BMC; 1.
DR   SMART; SM00877; BMC; 1.
DR   SUPFAM; SSF143414; SSF143414; 1.
DR   PROSITE; PS01139; BMC_1; 1.
DR   PROSITE; PS51930; BMC_2; 1.
PE   3: Inferred from homology;
KW   Bacterial microcompartment; Transport.
FT   CHAIN           1..94
FT                   /note="Bacterial microcompartment shell protein PduA"
FT                   /id="PRO_0000201510"
FT   DOMAIN          5..89
FT                   /note="BMC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01278"
SQ   SEQUENCE   94 AA;  9592 MW;  5EDC7C793F19DE1E CRC64;
     MQQEALGMVE TKGLTAAIEA ADAMVKSANV MLVGYEKIGS GLVTVIVRGD VGAVKAATDA
     GAAAARNVGE VKAVHVIPRP HTDVEKILPK GISQ