ID   ASR_ECOL6               Reviewed;         102 AA.
AC   Q8CW15;
DT   30-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2003, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Acid shock protein {ECO:0000255|HAMAP-Rule:MF_00546};
DE   Flags: Precursor;
GN   Name=asr {ECO:0000255|HAMAP-Rule:MF_00546}; OrderedLocusNames=c1988;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Required for growth and/or survival at acidic conditions.
CC       {ECO:0000255|HAMAP-Rule:MF_00546}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00546}.
CC   -!- PTM: Proteolytic processing gives rise to the active protein.
CC       {ECO:0000255|HAMAP-Rule:MF_00546}.
CC   -!- SIMILARITY: Belongs to the Asr family. {ECO:0000255|HAMAP-
CC       Rule:MF_00546}.
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DR   EMBL; AE014075; AAN80448.1; -; Genomic_DNA.
DR   RefSeq; WP_001362115.1; NZ_CP051263.1.
DR   AlphaFoldDB; Q8CW15; -.
DR   STRING; 199310.c1988; -.
DR   EnsemblBacteria; AAN80448; AAN80448; c1988.
DR   GeneID; 58459793; -.
DR   KEGG; ecc:c1988; -.
DR   eggNOG; ENOG5032U9T; Bacteria.
DR   HOGENOM; CLU_102486_2_0_6; -.
DR   OMA; TTHVKKH; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_00546; Asr; 1.
DR   InterPro; IPR023497; Acid_shock.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00546"
FT   PROPEP          22..58
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00546"
FT                   /id="PRO_0000269504"
FT   CHAIN           59..102
FT                   /note="Acid shock protein"
FT                   /id="PRO_0000002403"
FT   REGION          22..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..67
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   102 AA;  10531 MW;  25881B45DBF214AE CRC64;
     MKKVLALVVA AAMGLSSAAF AAETATTPAP TATTTKAAPA KTTHHKKQHK AAPAQKAQAA
     KKHHKNAKAE QKAPEQKAQA AKKHAKKHSH QQPAKPAAQP AA