PDXH_SCHPO
ID PDXH_SCHPO Reviewed; 190 AA.
AC Q9UUK0;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Pyridoxamine 5'-phosphate oxidase C1952.08c homolog;
DE AltName: Full=PNP/PMP oxidase C1952.08c homolog;
DE Short=PNPOx C1952.08c homolog;
GN ORFNames=SPAC1952.08c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000250};
CC Note=Binds 1 FMN per subunit. {ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the pyridoxamine 5'-phosphate oxidase family.
CC {ECO:0000305}.
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DR EMBL; CU329670; CAB52572.1; -; Genomic_DNA.
DR PIR; T37936; T37936.
DR RefSeq; NP_594810.1; NM_001020239.2.
DR AlphaFoldDB; Q9UUK0; -.
DR SMR; Q9UUK0; -.
DR BioGRID; 279028; 1.
DR iPTMnet; Q9UUK0; -.
DR MaxQB; Q9UUK0; -.
DR PaxDb; Q9UUK0; -.
DR PRIDE; Q9UUK0; -.
DR EnsemblFungi; SPAC1952.08c.1; SPAC1952.08c.1:pep; SPAC1952.08c.
DR GeneID; 2542572; -.
DR KEGG; spo:SPAC1952.08c; -.
DR PomBase; SPAC1952.08c; -.
DR VEuPathDB; FungiDB:SPAC1952.08c; -.
DR eggNOG; ENOG502S6QN; Eukaryota.
DR HOGENOM; CLU_078856_0_0_1; -.
DR InParanoid; Q9UUK0; -.
DR OMA; HDWISAN; -.
DR PhylomeDB; Q9UUK0; -.
DR PRO; PR:Q9UUK0; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0004733; F:pyridoxamine-phosphate oxidase activity; ISM:PomBase.
DR GO; GO:0042818; P:pyridoxamine metabolic process; ISM:PomBase.
DR Gene3D; 2.30.110.10; -; 1.
DR InterPro; IPR011576; Pyridox_Oxase_put.
DR InterPro; IPR012349; Split_barrel_FMN-bd.
DR Pfam; PF01243; Putative_PNPOx; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Flavoprotein; FMN; Nucleus; Reference proteome.
FT CHAIN 1..190
FT /note="Pyridoxamine 5'-phosphate oxidase C1952.08c homolog"
FT /id="PRO_0000315948"
FT BINDING 62
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000250"
FT BINDING 69
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000250"
SQ SEQUENCE 190 AA; 21653 MW; 318B80A5F08693C1 CRC64;
MASKVDSSHE FPSQIKRCLS SSKYIQLATC FHDQPHSSLM TFTYLPAGSA APYEVEDCII
LSTGENSKKY FNISSNPRVS LLVHDWTTNR QETDPDASSL YTLLYKMNQA QFSNTSVTLN
GLATVLPKNS KEEEFFREKH LNTNDKGNTK QYVEGEDMRI IKIKLESARI CDQRLNNVQK
WNARGDETPF
