PDZ11_DANRE
ID PDZ11_DANRE Reviewed; 142 AA.
AC Q6NXB2;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=PDZ domain-containing protein 11;
GN Name=pdzd11; Synonyms=pdzk11; ORFNames=zgc:77536;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q5EBL8}.
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DR EMBL; BC067163; AAH67163.1; -; mRNA.
DR RefSeq; NP_998122.1; NM_212957.1.
DR AlphaFoldDB; Q6NXB2; -.
DR SMR; Q6NXB2; -.
DR STRING; 7955.ENSDARP00000069672; -.
DR PaxDb; Q6NXB2; -.
DR Ensembl; ENSDART00000075187; ENSDARP00000069672; ENSDARG00000053194.
DR Ensembl; ENSDART00000130680; ENSDARP00000111909; ENSDARG00000053194.
DR Ensembl; ENSDART00000187113; ENSDARP00000155288; ENSDARG00000116591.
DR GeneID; 405893; -.
DR KEGG; dre:405893; -.
DR CTD; 51248; -.
DR ZFIN; ZDB-GENE-040426-2544; pdzd11.
DR eggNOG; KOG3528; Eukaryota.
DR GeneTree; ENSGT00940000153222; -.
DR HOGENOM; CLU_133335_0_0_1; -.
DR InParanoid; Q6NXB2; -.
DR OMA; ERIYHSD; -.
DR OrthoDB; 1530562at2759; -.
DR PhylomeDB; Q6NXB2; -.
DR TreeFam; TF318964; -.
DR Reactome; R-DRE-196780; Biotin transport and metabolism.
DR Reactome; R-DRE-199220; Vitamin B5 (pantothenate) metabolism.
DR Reactome; R-DRE-425397; Transport of vitamins, nucleosides, and related molecules.
DR Reactome; R-DRE-6803544; Ion influx/efflux at host-pathogen interface.
DR Reactome; R-DRE-936837; Ion transport by P-type ATPases.
DR PRO; PR:Q6NXB2; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 14.
DR Bgee; ENSDARG00000053194; Expressed in brain and 28 other tissues.
DR ExpressionAtlas; Q6NXB2; baseline.
DR GO; GO:0016323; C:basolateral plasma membrane; ISS:UniProtKB.
DR GO; GO:0005911; C:cell-cell junction; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; ISS:UniProtKB.
DR GO; GO:0098793; C:presynapse; IEA:GOC.
DR GO; GO:0045202; C:synapse; IBA:GO_Central.
DR GO; GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
DR GO; GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IBA:GO_Central.
DR GO; GO:0007269; P:neurotransmitter secretion; IBA:GO_Central.
DR GO; GO:1903361; P:protein localization to basolateral plasma membrane; IBA:GO_Central.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; SSF50156; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..142
FT /note="PDZ domain-containing protein 11"
FT /id="PRO_0000058271"
FT DOMAIN 49..131
FT /note="PDZ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
SQ SEQUENCE 142 AA; 16424 MW; 011BE42F2818FE9C CRC64;
MDQKIPYDDY QLPVVFLPSY ENPPAWIPPQ ERIHHPDYNN ELAQFLPRTI VLKKPPGAQL
GFNIRGGKAS QLGIFISKVV PDSDAHRAGL QEGDQVLSVN EVDFQDIEHS RAVEILKTAR
EILMKVRYFP YNYQRQKERT VH