PDZ1I_PIG
ID PDZ1I_PIG Reviewed; 114 AA.
AC Q6ITQ4;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=PDZK1-interacting protein 1;
DE AltName: Full=17 kDa membrane-associated protein;
GN Name=PDZK1IP1; Synonyms=MAP17;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Kidney;
RA Carrodeguas J.A., Catalan J., Sorribas V.;
RT "Pig MAP17 cloned from LLC-PK1 cells.";
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts with PDZK1. Forms a heterodimer with SLC5A2; this
CC interaction enhances SLC5A2 transporter activity over a hundred-fold.
CC {ECO:0000250|UniProtKB:Q13113}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass membrane
CC protein {ECO:0000250}.
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DR EMBL; AY626348; AAT41665.1; -; mRNA.
DR RefSeq; NP_001001769.1; NM_001001769.1.
DR AlphaFoldDB; Q6ITQ4; -.
DR SMR; Q6ITQ4; -.
DR STRING; 9823.ENSSSCP00000004061; -.
DR PaxDb; Q6ITQ4; -.
DR PRIDE; Q6ITQ4; -.
DR Ensembl; ENSSSCT00025031137; ENSSSCP00025013097; ENSSSCG00025022966.
DR Ensembl; ENSSSCT00035048254; ENSSSCP00035019294; ENSSSCG00035036413.
DR Ensembl; ENSSSCT00045042507; ENSSSCP00045029519; ENSSSCG00045024957.
DR Ensembl; ENSSSCT00050082010; ENSSSCP00050035212; ENSSSCG00050060196.
DR Ensembl; ENSSSCT00055029941; ENSSSCP00055023845; ENSSSCG00055015211.
DR Ensembl; ENSSSCT00065051431; ENSSSCP00065022326; ENSSSCG00065037667.
DR GeneID; 414756; -.
DR KEGG; ssc:414756; -.
DR CTD; 10158; -.
DR eggNOG; ENOG502SAPW; Eukaryota.
DR InParanoid; Q6ITQ4; -.
DR OrthoDB; 1588365at2759; -.
DR Proteomes; UP000008227; Unplaced.
DR Proteomes; UP000314985; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR026628; PDZK-int_prot1.
DR InterPro; IPR031627; PDZK1IP1/SMIM24.
DR PANTHER; PTHR15296; PTHR15296; 1.
DR PANTHER; PTHR15296:SF0; PTHR15296:SF0; 1.
DR Pfam; PF15807; MAP17; 1.
PE 3: Inferred from homology;
KW Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..114
FT /note="PDZK1-interacting protein 1"
FT /id="PRO_0000058284"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 92..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 85
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9CQH0"
SQ SEQUENCE 114 AA; 12401 MW; F91BDFE26DCB0BB6 CRC64;
MSALSLVILG LLMAVPPASC QQGLGNLQPW MQGLIAVAVF LVLVAIAFAI NHFWCQEERE
PMNMVMTTGN KADGILIGTE GKYSSMAASF RSNEHENAYE NTSEEEGRVH STPM