PDZ1I_RAT
ID PDZ1I_RAT Reviewed; 114 AA.
AC Q923S2;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=PDZK1-interacting protein 1;
DE AltName: Full=17 kDa membrane-associated protein;
GN Name=Pdzk1ip1; Synonyms=Map17;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Wistar;
RX PubMed=12812916; DOI=10.1152/ajprenal.00149.2003;
RA Blasco T., Aramayona J.J., Alcalde A.I., Catalan J., Sarasa M.,
RA Sorribas V.;
RT "Rat kidney MAP17 induces cotransport of Na-mannose and Na-glucose in
RT Xenopus laevis oocytes.";
RL Am. J. Physiol. 285:F799-F810(2003).
CC -!- SUBUNIT: Interacts with PDZK1. Forms a heterodimer with SLC5A2; this
CC interaction enhances SLC5A2 transporter activity over a hundred-fold.
CC {ECO:0000250|UniProtKB:Q13113}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass membrane
CC protein {ECO:0000250}.
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DR EMBL; AF402772; AAK94063.1; -; mRNA.
DR RefSeq; NP_569085.1; NM_130401.1.
DR RefSeq; XP_006238682.1; XM_006238620.3.
DR RefSeq; XP_008762191.1; XM_008763969.2.
DR AlphaFoldDB; Q923S2; -.
DR SMR; Q923S2; -.
DR STRING; 10116.ENSRNOP00000011434; -.
DR iPTMnet; Q923S2; -.
DR PhosphoSitePlus; Q923S2; -.
DR PaxDb; Q923S2; -.
DR PRIDE; Q923S2; -.
DR GeneID; 81916; -.
DR KEGG; rno:81916; -.
DR UCSC; RGD:620952; rat.
DR CTD; 10158; -.
DR RGD; 620952; Pdzk1ip1.
DR VEuPathDB; HostDB:ENSRNOG00000008161; -.
DR eggNOG; ENOG502SAPW; Eukaryota.
DR HOGENOM; CLU_168651_0_0_1; -.
DR InParanoid; Q923S2; -.
DR OMA; NFRSSEH; -.
DR OrthoDB; 1588365at2759; -.
DR PhylomeDB; Q923S2; -.
DR TreeFam; TF328829; -.
DR PRO; PR:Q923S2; -.
DR Proteomes; UP000002494; Chromosome 5.
DR Bgee; ENSRNOG00000008161; Expressed in adult mammalian kidney and 14 other tissues.
DR Genevisible; Q923S2; RN.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR026628; PDZK-int_prot1.
DR InterPro; IPR031627; PDZK1IP1/SMIM24.
DR PANTHER; PTHR15296; PTHR15296; 1.
DR PANTHER; PTHR15296:SF0; PTHR15296:SF0; 1.
DR Pfam; PF15807; MAP17; 1.
PE 3: Inferred from homology;
KW Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..114
FT /note="PDZK1-interacting protein 1"
FT /id="PRO_0000058286"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOD_RES 85
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9CQH0"
SQ SEQUENCE 114 AA; 12243 MW; D207C0190313ED48 CRC64;
MLALSLLALG LLAEVAPASC QQGLGNLQPW MQGLIAVAVF LVLVAIAFAV NHFWCQEEQE
PGSTMMITGN KADGVLVGMD GRYSSMASGF RSSEHKNAFE NVLEEEGRVR STPM