PDZD9_MOUSE
ID PDZD9_MOUSE Reviewed; 266 AA.
AC Q9D9M4; Q9CR71;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=PDZ domain-containing protein 9;
GN Name=Pdzd9;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP STRUCTURE BY NMR OF 8-120.
RG RIKEN structural genomics initiative (RSGI);
RT "The solution structure of RSGI RUH-020, a PDZ domain of hypothetical
RT protein from mouse.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AK005921; BAB24317.1; -; mRNA.
DR EMBL; AK006727; BAB24716.1; -; mRNA.
DR EMBL; AK017019; BAB30553.1; -; mRNA.
DR CCDS; CCDS40110.1; -.
DR RefSeq; NP_001035226.1; NM_001040136.2.
DR RefSeq; XP_011240188.1; XM_011241886.2.
DR PDB; 1WIF; NMR; -; A=8-120.
DR PDBsum; 1WIF; -.
DR AlphaFoldDB; Q9D9M4; -.
DR SMR; Q9D9M4; -.
DR STRING; 10090.ENSMUSP00000033178; -.
DR PaxDb; Q9D9M4; -.
DR PRIDE; Q9D9M4; -.
DR ProteomicsDB; 287819; -.
DR Antibodypedia; 25794; 59 antibodies from 13 providers.
DR Ensembl; ENSMUST00000033178; ENSMUSP00000033178; ENSMUSG00000030887.
DR GeneID; 67983; -.
DR UCSC; uc009jmu.1; mouse.
DR CTD; 255762; -.
DR MGI; MGI:1915233; Pdzd9.
DR VEuPathDB; HostDB:ENSMUSG00000030887; -.
DR eggNOG; ENOG502RYRV; Eukaryota.
DR GeneTree; ENSGT00390000008326; -.
DR HOGENOM; CLU_095719_0_0_1; -.
DR InParanoid; Q9D9M4; -.
DR OMA; GYKKKNR; -.
DR OrthoDB; 1459151at2759; -.
DR PhylomeDB; Q9D9M4; -.
DR TreeFam; TF337738; -.
DR BioGRID-ORCS; 67983; 3 hits in 71 CRISPR screens.
DR ChiTaRS; Pdzd9; mouse.
DR EvolutionaryTrace; Q9D9M4; -.
DR PRO; PR:Q9D9M4; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q9D9M4; protein.
DR Bgee; ENSMUSG00000030887; Expressed in spermatid and 38 other tissues.
DR ExpressionAtlas; Q9D9M4; baseline and differential.
DR Genevisible; Q9D9M4; MM.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR039179; PDZD9.
DR PANTHER; PTHR22698; PTHR22698; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; SSF50156; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..266
FT /note="PDZ domain-containing protein 9"
FT /id="PRO_0000271217"
FT DOMAIN 27..109
FT /note="PDZ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT CONFLICT 37
FT /note="N -> T (in Ref. 1; BAB24716)"
FT /evidence="ECO:0000305"
FT CONFLICT 189
FT /note="K -> M (in Ref. 1; BAB24716)"
FT /evidence="ECO:0000305"
FT CONFLICT 216..217
FT /note="AP -> RT (in Ref. 1; BAB24716)"
FT /evidence="ECO:0000305"
FT STRAND 10..12
FT /evidence="ECO:0007829|PDB:1WIF"
FT STRAND 28..34
FT /evidence="ECO:0007829|PDB:1WIF"
FT STRAND 44..47
FT /evidence="ECO:0007829|PDB:1WIF"
FT STRAND 50..53
FT /evidence="ECO:0007829|PDB:1WIF"
FT HELIX 62..64
FT /evidence="ECO:0007829|PDB:1WIF"
FT STRAND 66..68
FT /evidence="ECO:0007829|PDB:1WIF"
FT STRAND 73..80
FT /evidence="ECO:0007829|PDB:1WIF"
FT HELIX 87..94
FT /evidence="ECO:0007829|PDB:1WIF"
FT STRAND 102..112
FT /evidence="ECO:0007829|PDB:1WIF"
FT TURN 116..118
FT /evidence="ECO:0007829|PDB:1WIF"
SQ SEQUENCE 266 AA; 29761 MW; 178DFFE4BFCAE51F CRC64;
MEKGSLKSKN EKEQLSKAKA SVSSLNKVIQ TKLTVGNLGL GLVVIQNGPY LQISHLINKG
AAASDGILQP GDVLISVGHA NVLGYTLREF LKLLQNITIG TVLQIKAYRG FLEIPQEWQD
VYDLIPETKF PIPHTPKKTE PARESLVKDD HEEAVLDKKL KYYRYPRSVW NHPVRTPISI
STEWHGYEKK ERTISVGRDI NSDVVIHKDD KKELRAPSPY WAMVEQDRAI SSSSSSTANS
SSSDAFWLED YAQVEEGNGK QVSKFG
