ID   PE15_MYCBO              Reviewed;         102 AA.
AC   P0A683; A0A1R3XZ68; P71656; X2BHR2;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=PE family immunomodulator PE15 {ECO:0000250|UniProtKB:P9WIH1};
GN   Name=PE15; OrderedLocusNames=BQ2027_MB1421;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WIH1}. Cell
CC       envelope {ECO:0000250|UniProtKB:P9WIH1}. Cell surface
CC       {ECO:0000250|UniProtKB:P9WIH1}. Note=Secreted via the ESX-3 / type VII
CC       secretion system (T7SS). {ECO:0000250|UniProtKB:P9WIH1}.
CC   -!- SIMILARITY: Belongs to the mycobacterial PE family. {ECO:0000305}.
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DR   EMBL; LT708304; SIU00024.1; -; Genomic_DNA.
DR   RefSeq; NP_855073.1; NC_002945.3.
DR   RefSeq; WP_003407225.1; NC_002945.4.
DR   AlphaFoldDB; P0A683; -.
DR   SMR; P0A683; -.
DR   EnsemblBacteria; SIU00024; SIU00024; BQ2027_MB1421.
DR   PATRIC; fig|233413.5.peg.1556; -.
DR   OMA; NYHAADT; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR   GO; GO:0031975; C:envelope; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000084; PE-PGRS_N.
DR   Pfam; PF00934; PE; 1.
PE   3: Inferred from homology;
KW   Secreted.
FT   CHAIN           1..102
FT                   /note="PE family immunomodulator PE15"
FT                   /id="PRO_0000023571"
FT   DOMAIN          3..91
FT                   /note="PE"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   102 AA;  9862 MW;  8165F09DBDB9D752 CRC64;
     MTLRVVPESL AGASAAIEAV TARLAAAHAA AAPFIAAVIP PGSDSVSVCN AVEFSVHGSQ
     HVAMAAQGVE ELGRSGVGVA ESGASYAARD ALAAASYLSG GL