ID   PEB1A_CAMJJ             Reviewed;         259 AA.
AC   A1VZQ4; P45678;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Major cell-binding factor;
DE   AltName: Full=CBF1;
DE   AltName: Full=PEB1;
DE   Flags: Precursor;
GN   Name=peb1A; Synonyms=pebA; OrderedLocusNames=CJJ81176_0928;
OS   Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Campylobacter.
OX   NCBI_TaxID=354242;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8360165; DOI=10.1016/s0021-9258(17)46689-0;
RA   Pei Z., Blaser M.J.;
RT   "PEB1, the major cell-binding factor of Campylobacter jejuni, is a homolog
RT   of the binding component in Gram-negative nutrient transport systems.";
RL   J. Biol. Chem. 268:18717-18725(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=81-176;
RA   Fouts D.E., Nelson K.E., Sebastian Y.;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Common antigen and a major cell adherence molecule. Most
CC       probably involved, with PEB1C, in a binding-protein-dependent transport
CC       system for an amino acid. May be involved in binding to intestinal
CC       cells.
CC   -!- SUBCELLULAR LOCATION: Cell surface.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 3 family.
CC       {ECO:0000305}.
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DR   EMBL; L13662; AAA02919.1; -; Unassigned_DNA.
DR   EMBL; CP000538; EAQ71888.1; -; Genomic_DNA.
DR   PIR; A48518; A48518.
DR   RefSeq; WP_002865903.1; NC_008787.1.
DR   AlphaFoldDB; A1VZQ4; -.
DR   SMR; A1VZQ4; -.
DR   STRING; 354242.CJJ81176_0928; -.
DR   EnsemblBacteria; EAQ71888; EAQ71888; CJJ81176_0928.
DR   KEGG; cjj:CJJ81176_0928; -.
DR   eggNOG; COG0834; Bacteria.
DR   HOGENOM; CLU_019602_18_4_7; -.
DR   OMA; YIAGIRM; -.
DR   Proteomes; UP000000646; Chromosome.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018313; SBP_3_CS.
DR   InterPro; IPR001638; Solute-binding_3/MltF_N.
DR   Pfam; PF00497; SBP_bac_3; 1.
DR   SMART; SM00062; PBPb; 1.
DR   PROSITE; PS01039; SBP_BACTERIAL_3; 1.
PE   3: Inferred from homology;
KW   Signal; Transport.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000250"
FT   CHAIN           27..259
FT                   /note="Major cell-binding factor"
FT                   /id="PRO_0000285823"
FT   CONFLICT        139
FT                   /note="N -> K (in Ref. 1; AAA02919)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   259 AA;  28164 MW;  D8632BCE87BBCED5 CRC64;
     MVFRKSLLKL AVFALGACVA FSNANAAEGK LESIKSKGQL IVGVKNDVPH YALLDQATGE
     IKGFEVDVAK LLAKSILGDD KKIKLVAVNA KTRGPLLDNG SVDAVIATFT ITPERKRIYN
     FSEPYYQDAI GLLVLKEKNY KSLADMKGAN IGVAQAATTK KAIGEAAKKI GIDVKFSEFP
     DYPSIKAALD AKRVDAFSVD KSILLGYVDD KSEILPDSFE PQSYGIVTKK DDPAFAKYVD
     DFVKEHKNEI DALAKKWGL