ID   PEBB_SYNPY              Reviewed;         257 AA.
AC   Q02190; Q93MM9;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   12-FEB-2003, sequence version 2.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Phycoerythrobilin:ferredoxin oxidoreductase;
DE            EC=1.3.7.3;
GN   Name=pebB;
OS   Synechococcus sp. (strain WH8020).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=32052;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8425055; DOI=10.1007/bf00019939;
RA   de Lorimier R., Wilbanks S.M., Glazer A.N.;
RT   "Genes of the R-phycocyanin II locus of marine Synechococcus spp., and
RT   comparison of protein-chromophore interactions in phycocyanins differing in
RT   bilin composition.";
RL   Plant Mol. Biol. 21:225-237(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8419325; DOI=10.1016/s0021-9258(18)54064-3;
RA   Wilbanks S.M., Glazer A.N.;
RT   "Rod structure of a phycoerythrin II-containing phycobilisome. I.
RT   Organization and sequence of the gene cluster encoding the major
RT   phycobiliprotein rod components in the genome of marine Synechococcus sp.
RT   WH8020.";
RL   J. Biol. Chem. 268:1226-1235(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11283349; DOI=10.2307/3871353;
RA   Frankenberg N., Mukougawa K., Kohchi T., Lagarias J.C.;
RT   "Functional genomic analysis of the HY2 family of ferredoxin-dependent
RT   bilin reductases from oxygenic photosynthetic organisms.";
RL   Plant Cell 13:965-978(2001).
CC   -!- FUNCTION: Catalyzes the two-electron reduction of the C2 and C3(1)
CC       diene system of 15,16-dihydrobiliverdin.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(3Z)-phycoerythrobilin + oxidized 2[4Fe-4S]-[ferredoxin] =
CC         15,16-dihydrobiliverdin + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin];
CC         Xref=Rhea:RHEA:22092, Rhea:RHEA-COMP:10002, Rhea:RHEA-COMP:10004,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:33722, ChEBI:CHEBI:33723,
CC         ChEBI:CHEBI:57438, ChEBI:CHEBI:57899; EC=1.3.7.3;
CC   -!- SIMILARITY: Belongs to the HY2 family. {ECO:0000305}.
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DR   EMBL; M95288; AAA27344.1; -; Genomic_DNA.
DR   EMBL; AF400985; AAK77916.1; -; Genomic_DNA.
DR   PIR; B46448; B46448.
DR   RefSeq; WP_048347954.1; NZ_CP011941.1.
DR   AlphaFoldDB; Q02190; -.
DR   SMR; Q02190; -.
DR   STRING; 32052.WB44_13635; -.
DR   BioCyc; MetaCyc:MON-13952; -.
DR   GO; GO:0050897; F:cobalt ion binding; IEA:InterPro.
DR   GO; GO:0050618; F:phycoerythrobilin:ferredoxin oxidoreductase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0010024; P:phytochromobilin biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00793; PebB; 1.
DR   InterPro; IPR009249; Ferredoxin-dep_bilin_Rdtase.
DR   InterPro; IPR022827; Phycoerythrobilin_Fdx_Rdtase.
DR   PANTHER; PTHR34557; PTHR34557; 1.
DR   Pfam; PF05996; Fe_bilin_red; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..257
FT                   /note="Phycoerythrobilin:ferredoxin oxidoreductase"
FT                   /id="PRO_0000216737"
FT   CONFLICT        100
FT                   /note="D -> G (in Ref. 1 and 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        111
FT                   /note="L -> F (in Ref. 1 and 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   257 AA;  29289 MW;  26D65B6E8E7BFE8C CRC64;
     MTNQRFKSTD PVNIEGWSWQ PFLEDAIKRL EGLNVEPYPV PDRFLQREDQ TGSKSKSIPV
     TTATWACKTE KFRQVRAACV SAGSAASVLN FVINPKSTYD LPFFGGDLVT LPAGHLLALD
     LQPAIKTDEV HTTHVWDRLI PIFERWRDQL PYGGPIPEEA QPFFSPGFLW TRLPLGEEGD
     ELIQSIVRPA FNDYLDLYLE LAASAERVTD ERSEVLLQGQ RKYTDYRAEK DPARGMLTRF
     HGSEWTEAYI HTVLFDL