PED1A_MOUSE
ID PED1A_MOUSE Reviewed; 449 AA.
AC Q6P1Z5; A2BI89;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=PC-esterase domain-containing protein 1A;
DE AltName: Full=Protein FAM113A;
GN Name=Pced1a; Synonyms=Fam113a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=129/Sv; TISSUE=Embryonic stem cell;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the PC-esterase family. {ECO:0000305}.
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DR EMBL; BX890605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC064802; AAH64802.1; -; mRNA.
DR CCDS; CCDS50711.1; -.
DR RefSeq; NP_001108013.1; NM_001114541.1.
DR RefSeq; NP_848877.2; NM_178762.4.
DR RefSeq; XP_017174462.1; XM_017318973.1.
DR AlphaFoldDB; Q6P1Z5; -.
DR STRING; 10090.ENSMUSP00000087009; -.
DR CarbonylDB; Q6P1Z5; -.
DR PhosphoSitePlus; Q6P1Z5; -.
DR PaxDb; Q6P1Z5; -.
DR PRIDE; Q6P1Z5; -.
DR Antibodypedia; 23331; 102 antibodies from 17 providers.
DR DNASU; 319513; -.
DR Ensembl; ENSMUST00000089581; ENSMUSP00000087009; ENSMUSG00000037773.
DR Ensembl; ENSMUST00000110277; ENSMUSP00000105906; ENSMUSG00000037773.
DR GeneID; 319513; -.
DR KEGG; mmu:319513; -.
DR UCSC; uc008miu.2; mouse.
DR CTD; 64773; -.
DR MGI; MGI:2442177; Pced1a.
DR VEuPathDB; HostDB:ENSMUSG00000037773; -.
DR eggNOG; ENOG502QVBZ; Eukaryota.
DR GeneTree; ENSGT00390000002231; -.
DR HOGENOM; CLU_053865_0_0_1; -.
DR InParanoid; Q6P1Z5; -.
DR OMA; LAGDHYF; -.
DR OrthoDB; 1041357at2759; -.
DR PhylomeDB; Q6P1Z5; -.
DR TreeFam; TF328972; -.
DR BioGRID-ORCS; 319513; 3 hits in 72 CRISPR screens.
DR ChiTaRS; Pced1a; mouse.
DR PRO; PR:Q6P1Z5; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q6P1Z5; protein.
DR Bgee; ENSMUSG00000037773; Expressed in epiblast (generic) and 178 other tissues.
DR Genevisible; Q6P1Z5; MM.
DR GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR InterPro; IPR026057; PC-Esterase.
DR Pfam; PF13839; PC-Esterase; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..449
FT /note="PC-esterase domain-containing protein 1A"
FT /id="PRO_0000079447"
FT CONFLICT 330
FT /note="P -> S (in Ref. 2; AAH64802)"
FT /evidence="ECO:0000305"
FT CONFLICT 338
FT /note="P -> S (in Ref. 2; AAH64802)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 449 AA; 51311 MW; 70B05DF78F202F65 CRC64;
MVFCLENEMP HRLLGSAMVH FHASEVQQLL HNKFVVILGD SIQRAVYKDL VLLLQKDTLL
TASQLKAKGE LSFEQDQLVA GGQLGELHNG TQYREVRQFC SGSGHHLVRF YFLTRVYSEY
LEDILEELSY GPAPDLVIIN SCLWDLSRYG RCSMESYREN LERVFVRMDQ VLPDSCLLVW
NLAMPLGERV TGGFLLPELQ PLAVSLRQDV VEGNFYSATL AGKHCFDVLD LHFHFRHAVR
HRHRDGVHWD QHAHRHLSHL LLAHVADAWG VELPKHDRLP DPWIEDWSEM DHSFQGSHKQ
PPDFREKLAL PLLPPFHLPP PMSFPYPLEP SPPPLFPPLP QDTPFFQGQP FPPYEFKYNA
MEDFSMPGCG PGMNFVPGPL PPSVSGPVSH GQHRGPVVHR GKPRCVLNNP YHVPRIGGPC
RHRLRHSDRL IHTYKQDRRG HAHSGTWPG