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PED1A_MOUSE
ID   PED1A_MOUSE             Reviewed;         449 AA.
AC   Q6P1Z5; A2BI89;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 2.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=PC-esterase domain-containing protein 1A;
DE   AltName: Full=Protein FAM113A;
GN   Name=Pced1a; Synonyms=Fam113a;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=129/Sv; TISSUE=Embryonic stem cell;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the PC-esterase family. {ECO:0000305}.
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DR   EMBL; BX890605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC064802; AAH64802.1; -; mRNA.
DR   CCDS; CCDS50711.1; -.
DR   RefSeq; NP_001108013.1; NM_001114541.1.
DR   RefSeq; NP_848877.2; NM_178762.4.
DR   RefSeq; XP_017174462.1; XM_017318973.1.
DR   AlphaFoldDB; Q6P1Z5; -.
DR   STRING; 10090.ENSMUSP00000087009; -.
DR   CarbonylDB; Q6P1Z5; -.
DR   PhosphoSitePlus; Q6P1Z5; -.
DR   PaxDb; Q6P1Z5; -.
DR   PRIDE; Q6P1Z5; -.
DR   Antibodypedia; 23331; 102 antibodies from 17 providers.
DR   DNASU; 319513; -.
DR   Ensembl; ENSMUST00000089581; ENSMUSP00000087009; ENSMUSG00000037773.
DR   Ensembl; ENSMUST00000110277; ENSMUSP00000105906; ENSMUSG00000037773.
DR   GeneID; 319513; -.
DR   KEGG; mmu:319513; -.
DR   UCSC; uc008miu.2; mouse.
DR   CTD; 64773; -.
DR   MGI; MGI:2442177; Pced1a.
DR   VEuPathDB; HostDB:ENSMUSG00000037773; -.
DR   eggNOG; ENOG502QVBZ; Eukaryota.
DR   GeneTree; ENSGT00390000002231; -.
DR   HOGENOM; CLU_053865_0_0_1; -.
DR   InParanoid; Q6P1Z5; -.
DR   OMA; LAGDHYF; -.
DR   OrthoDB; 1041357at2759; -.
DR   PhylomeDB; Q6P1Z5; -.
DR   TreeFam; TF328972; -.
DR   BioGRID-ORCS; 319513; 3 hits in 72 CRISPR screens.
DR   ChiTaRS; Pced1a; mouse.
DR   PRO; PR:Q6P1Z5; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; Q6P1Z5; protein.
DR   Bgee; ENSMUSG00000037773; Expressed in epiblast (generic) and 178 other tissues.
DR   Genevisible; Q6P1Z5; MM.
DR   GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR   InterPro; IPR026057; PC-Esterase.
DR   Pfam; PF13839; PC-Esterase; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..449
FT                   /note="PC-esterase domain-containing protein 1A"
FT                   /id="PRO_0000079447"
FT   CONFLICT        330
FT                   /note="P -> S (in Ref. 2; AAH64802)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        338
FT                   /note="P -> S (in Ref. 2; AAH64802)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   449 AA;  51311 MW;  70B05DF78F202F65 CRC64;
     MVFCLENEMP HRLLGSAMVH FHASEVQQLL HNKFVVILGD SIQRAVYKDL VLLLQKDTLL
     TASQLKAKGE LSFEQDQLVA GGQLGELHNG TQYREVRQFC SGSGHHLVRF YFLTRVYSEY
     LEDILEELSY GPAPDLVIIN SCLWDLSRYG RCSMESYREN LERVFVRMDQ VLPDSCLLVW
     NLAMPLGERV TGGFLLPELQ PLAVSLRQDV VEGNFYSATL AGKHCFDVLD LHFHFRHAVR
     HRHRDGVHWD QHAHRHLSHL LLAHVADAWG VELPKHDRLP DPWIEDWSEM DHSFQGSHKQ
     PPDFREKLAL PLLPPFHLPP PMSFPYPLEP SPPPLFPPLP QDTPFFQGQP FPPYEFKYNA
     MEDFSMPGCG PGMNFVPGPL PPSVSGPVSH GQHRGPVVHR GKPRCVLNNP YHVPRIGGPC
     RHRLRHSDRL IHTYKQDRRG HAHSGTWPG
 
 
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