PED1B_MOUSE
ID PED1B_MOUSE Reviewed; 433 AA.
AC Q8BGX1; Q5RK34;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=PC-esterase domain-containing protein 1B;
DE AltName: Full=Protein FAM113B;
GN Name=Pced1b; Synonyms=Fam113b;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Spinal ganglion;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J, and FVB/N; TISSUE=Embryo, and Salivary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the PC-esterase family. {ECO:0000305}.
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DR EMBL; AK051480; BAC34656.1; -; mRNA.
DR EMBL; BC038822; AAH38822.1; -; mRNA.
DR EMBL; BC086317; AAH86317.1; -; mRNA.
DR CCDS; CCDS27781.1; -.
DR RefSeq; NP_758497.1; NM_172293.4.
DR RefSeq; XP_006521026.1; XM_006520963.3.
DR RefSeq; XP_006521027.1; XM_006520964.3.
DR RefSeq; XP_006521028.1; XM_006520965.3.
DR RefSeq; XP_006521030.1; XM_006520967.3.
DR RefSeq; XP_006521031.1; XM_006520968.3.
DR RefSeq; XP_011243926.1; XM_011245624.2.
DR RefSeq; XP_011243927.1; XM_011245625.2.
DR RefSeq; XP_011243928.1; XM_011245626.2.
DR AlphaFoldDB; Q8BGX1; -.
DR STRING; 10090.ENSMUSP00000055485; -.
DR iPTMnet; Q8BGX1; -.
DR PhosphoSitePlus; Q8BGX1; -.
DR EPD; Q8BGX1; -.
DR MaxQB; Q8BGX1; -.
DR PaxDb; Q8BGX1; -.
DR PRIDE; Q8BGX1; -.
DR ProteomicsDB; 289344; -.
DR Antibodypedia; 49373; 24 antibodies from 12 providers.
DR DNASU; 239647; -.
DR Ensembl; ENSMUST00000059433; ENSMUSP00000055485; ENSMUSG00000044250.
DR Ensembl; ENSMUST00000228521; ENSMUSP00000154814; ENSMUSG00000044250.
DR GeneID; 239647; -.
DR KEGG; mmu:239647; -.
DR UCSC; uc007xkt.2; mouse.
DR CTD; 91523; -.
DR MGI; MGI:2446270; Pced1b.
DR VEuPathDB; HostDB:ENSMUSG00000044250; -.
DR eggNOG; ENOG502QVBZ; Eukaryota.
DR GeneTree; ENSGT00390000002231; -.
DR HOGENOM; CLU_053865_0_0_1; -.
DR InParanoid; Q8BGX1; -.
DR OMA; RGPYVPW; -.
DR OrthoDB; 1041357at2759; -.
DR PhylomeDB; Q8BGX1; -.
DR TreeFam; TF328972; -.
DR BioGRID-ORCS; 239647; 9 hits in 72 CRISPR screens.
DR ChiTaRS; Pced1b; mouse.
DR PRO; PR:Q8BGX1; -.
DR Proteomes; UP000000589; Chromosome 15.
DR RNAct; Q8BGX1; protein.
DR Bgee; ENSMUSG00000044250; Expressed in secondary oocyte and 104 other tissues.
DR ExpressionAtlas; Q8BGX1; baseline and differential.
DR Genevisible; Q8BGX1; MM.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR036514; SGNH_hydro_sf.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..433
FT /note="PC-esterase domain-containing protein 1B"
FT /id="PRO_0000331357"
FT REGION 386..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 220
FT /note="F -> S (in Ref. 2; AAH86317)"
FT /evidence="ECO:0000305"
FT CONFLICT 275
FT /note="S -> G (in Ref. 2; AAH86317)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 433 AA; 49968 MW; 672D5816AF1CF102 CRC64;
MVRLLASEVQ QLLHNKFVVV LGDSVHRAVY KDLVLLLQKD CLLTNKQLRT KGELSFEKDQ
LKMGGELDTL HNRTDYREVR EFCSDHHLVR FYFLTRVYSE YMESVLEELQ SGNHAPDVII
MNSCLWDVSR YGRNSLSSYK QNLENLFGRM DQVLPKSCLL VWNTAMPLGD KIKAAFLPQK
CKGQYPRISV ATLKRKVTQA NLYSHAEATK HYFDVLDLNF HFRQARKHLQ GDGVHWNEHA
HRKLSYLLLA HMADAWGVEL PQRDSWEPDF EAWESSGQVE ERQPQDNLGP QVFAPSPHCP
FRPPPLLPSP GLPIRPPPLL GCPLPQPQQM PPFPLYPQVS YFSSDPVFQS DEFYIHSDSP
PPTHTGYAFE GDFSFYPQPP VPNFRPPCHQ RQAPVVHRGF PRHFARGPYS NPWRDRPRRP
PKHSPAGLES RPQ
