ID   PEM5_PHACH              Reviewed;          20 AA.
AC   Q9URB1;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   29-SEP-2021, entry version 37.
DE   RecName: Full=Manganese peroxidase H5;
DE            EC=1.11.1.13;
DE   AltName: Full=Peroxidase manganese-dependent H5;
DE   Flags: Fragment;
OS   Phanerodontia chrysosporium (White-rot fungus) (Sporotrichum pruinosum).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Phanerochaetaceae; Phanerodontia.
OX   NCBI_TaxID=2822231;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=1592808; DOI=10.1128/jb.174.11.3532-3540.1992;
RA   Pease E.A., Tien M.;
RT   "Heterogeneity and regulation of manganese peroxidases from Phanerochaete
RT   chrysosporium.";
RL   J. Bacteriol. 174:3532-3540(1992).
CC   -!- FUNCTION: Catalyzes the oxidation of Mn(2+) to Mn(3+). The latter,
CC       acting as a diffusible redox mediator, is capable of oxidizing a
CC       variety of lignin compounds.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O2 + 2 Mn(2+) = 2 H2O + 2 Mn(3+);
CC         Xref=Rhea:RHEA:22776, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16240, ChEBI:CHEBI:29035, ChEBI:CHEBI:29041;
CC         EC=1.11.1.13;
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the peroxidase family. Ligninase subfamily.
CC       {ECO:0000305}.
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DR   PIR; C44907; C44907.
DR   SABIO-RK; Q9URB1; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016689; F:manganese peroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046274; P:lignin catabolic process; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hydrogen peroxide; Iron; Lignin degradation;
KW   Manganese; Metal-binding; Oxidoreductase; Peroxidase; Secreted.
FT   CHAIN           <1..>20
FT                   /note="Manganese peroxidase H5"
FT                   /id="PRO_0000055614"
FT   NON_TER         1
FT   NON_TER         20
SQ   SEQUENCE   20 AA;  2048 MW;  A11F41833CF2A933 CRC64;
     AVXHPGTXVS XAAXXXFIPL