ID   PEN3N_PENST             Reviewed;          75 AA.
AC   Q962B0;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Penaeidin-3n;
DE            Short=Pen-3n;
DE   Flags: Precursor;
OS   Penaeus setiferus (Atlantic white shrimp) (Litopenaeus setiferus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC   Penaeoidea; Penaeidae; Penaeus.
OX   NCBI_TaxID=64468;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Hemocyte;
RX   PubMed=12242595; DOI=10.1007/s00251-002-0487-z;
RA   Cuthbertson B.J., Shepard E.F., Chapman R.W., Gross P.S.;
RT   "Diversity of the penaeidin antimicrobial peptides in two shrimp species.";
RL   Immunogenetics 54:442-445(2002).
CC   -!- FUNCTION: Antibacterial and antifungal activity. Presents chitin-
CC       binding activity (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic granule. Note=Cytoplasmic granules of
CC       hemocytes and to a lesser extent in small granules of hemocytes.
CC   -!- SIMILARITY: Belongs to the penaeidin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY039204; AAK83452.1; -; mRNA.
DR   AlphaFoldDB; Q962B0; -.
DR   SMR; Q962B0; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR009226; Penaeidin.
DR   Pfam; PF05927; Penaeidin; 1.
PE   3: Inferred from homology;
KW   Amidation; Antibiotic; Antimicrobial; Chitin-binding; Disulfide bond;
KW   Fungicide; Pyrrolidone carboxylic acid; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..74
FT                   /note="Penaeidin-3n"
FT                   /id="PRO_0000023519"
FT   MOD_RES         20
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         74
FT                   /note="Serine amide"
FT                   /evidence="ECO:0000250"
FT   DISULFID        44..59
FT                   /evidence="ECO:0000250"
FT   DISULFID        48..66
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   75 AA;  8207 MW;  ACD53AB37AA4BBE6 CRC64;
     MRLVVCLVFL ASFALVCQGQ GYKGPYTRPI LRPYVRPVVS YNACTLSCRG ITTTQARSCS
     TRLGRCCHVA KGYSG