ID   PEP2_ARATH              Reviewed;         109 AA.
AC   Q9LV88; Q8L902;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Elicitor peptide 2;
DE   Flags: Precursor;
GN   Name=PEP2; Synonyms=PROPEP2; OrderedLocusNames=At5g64890; ORFNames=MXK3.12;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT   features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:31-63(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16785434; DOI=10.1073/pnas.0603727103;
RA   Huffaker A., Pearce G., Ryan C.A.;
RT   "An endogenous peptide signal in Arabidopsis activates components of the
RT   innate immune response.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:10098-10103(2006).
CC   -!- FUNCTION: Elicitor of plant defense. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the brassicaceae elicitor peptide family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB019236; BAA97301.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED97965.1; -; Genomic_DNA.
DR   EMBL; AY088708; AAM67027.1; -; mRNA.
DR   EMBL; BT024677; ABD57502.1; -; mRNA.
DR   RefSeq; NP_569000.1; NM_125887.3.
DR   AlphaFoldDB; Q9LV88; -.
DR   STRING; 3702.AT5G64890.1; -.
DR   MetOSite; Q9LV88; -.
DR   PaxDb; Q9LV88; -.
DR   PRIDE; Q9LV88; -.
DR   EnsemblPlants; AT5G64890.1; AT5G64890.1; AT5G64890.
DR   GeneID; 836612; -.
DR   Gramene; AT5G64890.1; AT5G64890.1; AT5G64890.
DR   KEGG; ath:AT5G64890; -.
DR   Araport; AT5G64890; -.
DR   TAIR; locus:2177644; AT5G64890.
DR   HOGENOM; CLU_174284_0_0_1; -.
DR   OMA; CLGILRH; -.
DR   OrthoDB; 1571343at2759; -.
DR   PhylomeDB; Q9LV88; -.
DR   PRO; PR:Q9LV88; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LV88; baseline and differential.
DR   Genevisible; Q9LV88; AT.
DR   GO; GO:0098542; P:defense response to other organism; IEP:TAIR.
DR   GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR   InterPro; IPR035176; PEP.
DR   Pfam; PF17232; Pep1_7; 1.
PE   3: Inferred from homology;
KW   Plant defense; Reference proteome.
FT   PROPEP          1..73
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000249081"
FT   PEPTIDE         74..109
FT                   /note="Elicitor peptide 2"
FT                   /id="PRO_0000249082"
FT   REGION          74..109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..89
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            90
FT                   /note="Required for ligand-receptor interaction"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        98
FT                   /note="V -> I (in Ref. 3; AAM67027)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   109 AA;  12343 MW;  63C5E26DBC71B32E CRC64;
     MEKLDKRREE ETYLWIPVQF LDQALIAVLK CIGLLCQPAK KTAPSPVTFN QPEEQEEDYG
     VALKDDDVVV LLRDNKAKSK KRDKEKPSSG RPGQTNSVPN AAIQVYKED