ID   PEP4_ARATH              Reviewed;          81 AA.
AC   Q9FIA9; Q8L9J1;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Elicitor peptide 4;
DE   Flags: Precursor;
GN   Name=PEP4; Synonyms=PROPEP4; OrderedLocusNames=At5g09980; ORFNames=MYH9.20;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA   Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT   features of the regions of 1,081,958 bp covered by seventeen physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:379-391(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16785434; DOI=10.1073/pnas.0603727103;
RA   Huffaker A., Pearce G., Ryan C.A.;
RT   "An endogenous peptide signal in Arabidopsis activates components of the
RT   innate immune response.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:10098-10103(2006).
CC   -!- FUNCTION: Elicitor of plant defense. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the brassicaceae elicitor peptide family.
CC       {ECO:0000305}.
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DR   EMBL; AB016893; BAB09419.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED91475.1; -; Genomic_DNA.
DR   EMBL; AY052255; AAK97725.1; -; mRNA.
DR   EMBL; AY060509; AAL31122.1; -; mRNA.
DR   EMBL; AY088403; AAM65940.1; -; mRNA.
DR   RefSeq; NP_568223.1; NM_121035.4.
DR   AlphaFoldDB; Q9FIA9; -.
DR   SMR; Q9FIA9; -.
DR   STRING; 3702.AT5G09980.1; -.
DR   PaxDb; Q9FIA9; -.
DR   PRIDE; Q9FIA9; -.
DR   ProteomicsDB; 235091; -.
DR   EnsemblPlants; AT5G09980.1; AT5G09980.1; AT5G09980.
DR   GeneID; 830859; -.
DR   Gramene; AT5G09980.1; AT5G09980.1; AT5G09980.
DR   KEGG; ath:AT5G09980; -.
DR   Araport; AT5G09980; -.
DR   TAIR; locus:2178218; AT5G09980.
DR   HOGENOM; CLU_2486520_0_0_1; -.
DR   InParanoid; Q9FIA9; -.
DR   OMA; LWIPFRF; -.
DR   OrthoDB; 1638710at2759; -.
DR   PRO; PR:Q9FIA9; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FIA9; baseline and differential.
DR   Genevisible; Q9FIA9; AT.
DR   GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR   GO; GO:0009753; P:response to jasmonic acid; IEP:TAIR.
DR   InterPro; IPR035176; PEP.
DR   Pfam; PF17232; Pep1_7; 1.
PE   3: Inferred from homology;
KW   Plant defense; Reference proteome.
FT   PROPEP          1..54
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000249085"
FT   PEPTIDE         55..81
FT                   /note="Elicitor peptide 4"
FT                   /id="PRO_0000249086"
FT   REGION          57..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            71
FT                   /note="Required for ligand-receptor interaction"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        58
FT                   /note="G -> V (in Ref. 4; AAM65940)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   81 AA;  9077 MW;  527E67E6E289FF52 CRC64;
     MERGVSYYLW IPFKFIHQTF GSLLLKLLGL RSPSDHSFPE DGEEEVKVVE VSSRGLPGKK
     NVLKKSRESS GKPGGTNKKP F