ID   PEP5L_SCHPO             Reviewed;         847 AA.
AC   P87295;
DT   15-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 2.
DT   25-MAY-2022, entry version 127.
DE   RecName: Full=Pep5-like zinc finger protein C16A10.03c;
GN   ORFNames=SPAC16A10.03c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   REVISION OF GENE MODEL.
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329670; CAB09996.4; -; Genomic_DNA.
DR   PIR; T37768; T37768.
DR   RefSeq; NP_594043.2; NM_001019468.2.
DR   AlphaFoldDB; P87295; -.
DR   BioGRID; 278774; 3.
DR   STRING; 4896.SPAC16A10.03c.1; -.
DR   iPTMnet; P87295; -.
DR   MaxQB; P87295; -.
DR   PaxDb; P87295; -.
DR   PRIDE; P87295; -.
DR   EnsemblFungi; SPAC16A10.03c.1; SPAC16A10.03c.1:pep; SPAC16A10.03c.
DR   GeneID; 2542307; -.
DR   KEGG; spo:SPAC16A10.03c; -.
DR   PomBase; SPAC16A10.03c; -.
DR   VEuPathDB; FungiDB:SPAC16A10.03c; -.
DR   eggNOG; KOG2114; Eukaryota.
DR   HOGENOM; CLU_333219_0_0_1; -.
DR   InParanoid; P87295; -.
DR   OMA; HRDCATE; -.
DR   PRO; PR:P87295; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0030897; C:HOPS complex; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IBA:GO_Central.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; ISM:PomBase.
DR   GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR   GO; GO:0007032; P:endosome organization; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:PomBase.
DR   GO; GO:0048284; P:organelle fusion; IBA:GO_Central.
DR   GO; GO:0070647; P:protein modification by small protein conjugation or removal; IC:PomBase.
DR   GO; GO:0007033; P:vacuole organization; IBA:GO_Central.
DR   GO; GO:0048278; P:vesicle docking; NAS:PomBase.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IBA:GO_Central.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR016528; VPS11.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001841; Znf_RING.
DR   PANTHER; PTHR23323:SF24; PTHR23323:SF24; 1.
DR   Pfam; PF17122; zf-C3H2C3; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50236; CHCR; 1.
PE   4: Predicted;
KW   Cytoplasm; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..847
FT                   /note="Pep5-like zinc finger protein C16A10.03c"
FT                   /id="PRO_0000055994"
FT   REPEAT          387..526
FT                   /note="CHCR"
FT   ZN_FING         780..814
FT                   /note="RING-type; atypical"
SQ   SEQUENCE   847 AA;  97486 MW;  E2D7C41540FD9BEE CRC64;
     MNINEWEKFS LFQWQECPSI KILHDSVGNK ISCIGKSTKR IAIGTLDGRI VILNSRLQLI
     RDFYACEQGI VQQIYITADQ SALCCVVLDK QNFVYLQFWS LNPSKKTNSN SPLCLYEHRL
     YGIPNPPFPA TSLYVSIDIK TVVCGFANGL VIRVEGDFVR DLGSRQDIIL REKDSITNLI
     LYSPKKLFVS TTTQVMVYKI KNNTKKVISN HGIPLFCSIQ YQGKYIMCAG GSFLSVYTTP
     DMQLQNTYCV DGTFELLFSS FGLVFVVYTR KNGENGLENN SSIREIKALD VEKRYVLYES
     LLEQSYDNIF FNSFDCIFFS STKVPCQLIR LPSDFVLCKM KGKKEHKDAF KIANYLGSPE
     DTIRECALAA AGECRQQLNF QDATYYYIEA IPFSDSAEII KFYLEKKLIK ELTSYLEALS
     AKGFAFSHEI STLIYLYIKL RKLDKLTEYV SGCPTEISLP ILRKYKCLDQ MELLGTIRKL
     PNVCMEVYQE KGDVEKAFNH LQVCNLPELL RTSNSFGIWL FNSDPMRFMK EAIRNIEILN
     SQGKDKELSN ILKIVYLGIF SQNVQIQLIF LDELLKSKKS ENVLKFIYTR KLYALMQKEL
     QHSNPQNELD ALQIIHDSQG LLDYESSILC LQAVSWKQVT DLLYSHLSLK EGQDDSLIQQ
     IISDPETVKT LSETYSSEDA LHVLKFFVRE RSITNKYEDI LYKILEACFM QFRIPIQHVL
     NILVKDGTLN FCFLKPLLLK WMNDYETRIH QNDDEIQVIK NDIEKKRQLL GTIQDSEKVC
     DNCEGLLDVP FVSYSCLHLV HRDCATETVC PKCKAGYLDK KNSHDQKKTS TFSELFHDFE
     SIDSVML