ID   PEP6_ARATH              Reviewed;         104 AA.
AC   Q9SIZ9;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Elicitor peptide 6;
DE   Flags: Precursor;
GN   Name=PEP6; Synonyms=PROPEP6; OrderedLocusNames=At2g22000; ORFNames=F7D8.32;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16785434; DOI=10.1073/pnas.0603727103;
RA   Huffaker A., Pearce G., Ryan C.A.;
RT   "An endogenous peptide signal in Arabidopsis activates components of the
RT   innate immune response.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:10098-10103(2006).
CC   -!- FUNCTION: Elicitor of plant defense. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the brassicaceae elicitor peptide family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC007019; AAD20417.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC07250.1; -; Genomic_DNA.
DR   EMBL; BT021966; AAY17403.1; -; mRNA.
DR   EMBL; BT024750; ABD59088.1; -; mRNA.
DR   PIR; G84607; G84607.
DR   RefSeq; NP_179791.1; NM_127769.3.
DR   AlphaFoldDB; Q9SIZ9; -.
DR   STRING; 3702.AT2G22000.1; -.
DR   PaxDb; Q9SIZ9; -.
DR   PRIDE; Q9SIZ9; -.
DR   ProteomicsDB; 236292; -.
DR   EnsemblPlants; AT2G22000.1; AT2G22000.1; AT2G22000.
DR   GeneID; 816736; -.
DR   Gramene; AT2G22000.1; AT2G22000.1; AT2G22000.
DR   KEGG; ath:AT2G22000; -.
DR   Araport; AT2G22000; -.
DR   TAIR; locus:2052561; AT2G22000.
DR   HOGENOM; CLU_2375752_0_0_1; -.
DR   InParanoid; Q9SIZ9; -.
DR   OMA; ETGFMAR; -.
DR   PRO; PR:Q9SIZ9; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9SIZ9; baseline and differential.
DR   Genevisible; Q9SIZ9; AT.
DR   GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR   InterPro; IPR035176; PEP.
DR   Pfam; PF17232; Pep1_7; 1.
PE   3: Inferred from homology;
KW   Plant defense; Reference proteome.
FT   PROPEP          1..81
FT                   /id="PRO_0000249089"
FT   PEPTIDE         82..104
FT                   /note="Elicitor peptide 6"
FT                   /id="PRO_0000249090"
FT   REGION          48..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        48..66
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            98
FT                   /note="Required for ligand-receptor interaction"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   104 AA;  11633 MW;  B00A462F6C7ED91E CRC64;
     MEVNGEEERR SRREDEEKED YYYSLLNSPC SVCNKFVQAI LKCLGLESSS IPPSSSSSSP
     SLVEEEDSGT ETVEETGFMA RITAVLRRRP RPPPYSSGRP GQNN