ID   PEPDA_LACLA             Reviewed;         459 AA.
AC   Q9CIV4;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Probable dipeptidase A;
DE            EC=3.4.13.19;
GN   Name=pepDA; OrderedLocusNames=LL0252; ORFNames=L48417;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid;
CC         Xref=Rhea:RHEA:48940, ChEBI:CHEBI:15377, ChEBI:CHEBI:59869,
CC         ChEBI:CHEBI:77460; EC=3.4.13.19;
CC   -!- SIMILARITY: Belongs to the peptidase C69 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE005176; AAK04350.1; -; Genomic_DNA.
DR   PIR; D86656; D86656.
DR   RefSeq; NP_266408.1; NC_002662.1.
DR   RefSeq; WP_010905239.1; NC_002662.1.
DR   AlphaFoldDB; Q9CIV4; -.
DR   SMR; Q9CIV4; -.
DR   STRING; 272623.L48417; -.
DR   MEROPS; C69.001; -.
DR   PaxDb; Q9CIV4; -.
DR   EnsemblBacteria; AAK04350; AAK04350; L48417.
DR   KEGG; lla:L48417; -.
DR   PATRIC; fig|272623.7.peg.277; -.
DR   eggNOG; COG4690; Bacteria.
DR   HOGENOM; CLU_014823_4_1_9; -.
DR   OMA; FVMSSHY; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0070004; F:cysteine-type exopeptidase activity; IEA:InterPro.
DR   GO; GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR005322; Peptidase_C69.
DR   PANTHER; PTHR12994; PTHR12994; 1.
DR   Pfam; PF03577; Peptidase_C69; 1.
PE   3: Inferred from homology;
KW   Dipeptidase; Hydrolase; Protease; Reference proteome.
FT   CHAIN           1..459
FT                   /note="Probable dipeptidase A"
FT                   /id="PRO_0000220382"
FT   ACT_SITE        3
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   459 AA;  51918 MW;  F6ABD66C8D37C1A1 CRC64;
     MTCTTFLVGK KASLDGTTLI ARNEDGGDKP NPQRFVVINP ENQPKHYRSI TTACEFDLPE
     NPLSYTSTPD ADSSYGIWAA AGINSENVAM TATETSTTNS RILGLDPYVE TGLGEEDFTT
     ITLPYIQSAR EGVERMGQLL EEYGTYESNG MAFSDKDEIW WLETLGGHQW AAIRIPDDAY
     VIAPNRLNID WYDFESSDTI YSTGLKEFID KNKLNPDFDG YNLRHIFGSS TIKDTRYNNP
     RAWYVQNYFS PETTGNDDPF NQDLPFICHA NRKISIEEIK FVMSSHYENT AYDPYSTTSS
     AAEQKLIRPI GLNRNLELHV LQIRDNIDKK LAGIHWLAFG PNSFNSLVPF YARVSDTPTC
     YRDTKADFDP TKMYWLTTMT AVLGDSNFQG YVDKRDNFDL NTMAKLRALQ NETDKVSDQS
     LEAVNEKLAQ IALTAQTELL GKMVISGSNH MKLRFDFND