ID   PEPDB_LACLA             Reviewed;         474 AA.
AC   Q9CFC3;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Probable dipeptidase B;
DE            EC=3.4.13.19;
GN   Name=pepDB; OrderedLocusNames=LL1558; ORFNames=L324;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid;
CC         Xref=Rhea:RHEA:48940, ChEBI:CHEBI:15377, ChEBI:CHEBI:59869,
CC         ChEBI:CHEBI:77460; EC=3.4.13.19;
CC   -!- SIMILARITY: Belongs to the peptidase C69 family. {ECO:0000305}.
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DR   EMBL; AE005176; AAK05656.1; -; Genomic_DNA.
DR   PIR; F86819; F86819.
DR   RefSeq; NP_267714.1; NC_002662.1.
DR   RefSeq; WP_003130696.1; NC_002662.1.
DR   AlphaFoldDB; Q9CFC3; -.
DR   SMR; Q9CFC3; -.
DR   STRING; 272623.L324; -.
DR   MEROPS; C69.001; -.
DR   PaxDb; Q9CFC3; -.
DR   EnsemblBacteria; AAK05656; AAK05656; L324.
DR   GeneID; 66442484; -.
DR   KEGG; lla:L324; -.
DR   PATRIC; fig|272623.7.peg.1676; -.
DR   eggNOG; COG4690; Bacteria.
DR   HOGENOM; CLU_014823_4_1_9; -.
DR   OMA; DLTYSHE; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0070004; F:cysteine-type exopeptidase activity; IEA:InterPro.
DR   GO; GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR005322; Peptidase_C69.
DR   PANTHER; PTHR12994; PTHR12994; 1.
DR   Pfam; PF03577; Peptidase_C69; 1.
PE   3: Inferred from homology;
KW   Dipeptidase; Hydrolase; Protease; Reference proteome.
FT   CHAIN           1..474
FT                   /note="Probable dipeptidase B"
FT                   /id="PRO_0000220383"
FT   ACT_SITE        11
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   474 AA;  53689 MW;  F5A0485FD26197A1 CRC64;
     MKIENRRKGS CTTVLVGRKA SIDGSTMIAR NDDGHEALDP QRFIVIQPEE QPRHYKAVLS
     DLELDLPENP LRYTSTPNAV LKEGIWPAAG INSANVAMSA TETITTNPRI LGLDPYVENG
     MGEEDLVTLV LPYIKSAREG VERLGQLLKT YGTYEPNGIA FADKEEVWWL ETIGGHHWAA
     VRIPDDSYVV APNRMNIDEF KFDNDDYMCS SDLKQLIDAN HLNPDFEGYE SHYNLRHIFG
     SSSIKDSVYN NPRTWYGQNF LGNPSEDPQN QELPFICEAS RKITVEDVKF VLSSHFENTK
     YDPYGSTNSP EERKLFRPIG INRNHSVHIL QVRNNVPDEL AGVQWLAFGA NTFNHVVPFY
     TAINDTPASY RDAKGEYDPT NMYWLSATTA VLGDSNYDLF VDLRNTFELN TMAKFHEIQN
     ETDKNFETAE DKIAYLTQAN EKLAEAAFKA QTELLGRMVV LGSANMKLRF DFND