ID   PEPR_LACDL              Reviewed;         333 AA.
AC   Q48544;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=HTH-type transcriptional regulator pepR1;
GN   Name=pepR1;
OS   Lactobacillus delbrueckii subsp. lactis.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=29397;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 7290;
RA   Stucky K., Schick J., Klein J.R., Henrich B., Plapp R.;
RL   Submitted (SEP-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional regulator of the pepQ gene for prolidase.
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DR   EMBL; Z54205; CAA90912.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q48544; -.
DR   SMR; Q48544; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   PRINTS; PR00036; HTHLACI.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   PROSITE; PS00356; HTH_LACI_1; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..333
FT                   /note="HTH-type transcriptional regulator pepR1"
FT                   /id="PRO_0000107975"
FT   DOMAIN          6..60
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT   DNA_BIND        8..27
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
SQ   SEQUENCE   333 AA;  36950 MW;  EE792627C09CB38F CRC64;
     MNKQDVTIYD VAREAKVSMA TVSRVVNGNN NVRKETRDRV MEVIKRLHYQ PNAVAQGLAS
     KRTTTVGLIV PDLTNLYFAE LSKGIDDIAV LYKYNIIISS VENRLMKEDA VIQGLLNKQV
     DGVIYMSNKL SEEAAEAFKR TDTPVVLAGT VSDNLEFPSV NIDYKKADTE ALNLLLNDGK
     KKLALIVGDK EASINRNYRI PAFEKFVADN ELEGCEIFDN IKDYSDGYNL YPELAKKGIN
     GAIITKDVSS VGLLNSALDR GAKVPEDFEI ITASATQIAS VVRPALTTIK QPLYDLGAVA
     MRMLTKLMND ESLEDKHIIL PYELIKKQST LNK