ID   A49_VACCC               Reviewed;         162 AA.
AC   P21068;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   23-FEB-2022, entry version 54.
DE   RecName: Full=Protein A49;
GN   ORFNames=A49R;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- SIMILARITY: Belongs to the poxviridae A49 protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M35027; AAA48181.1; -; Genomic_DNA.
DR   PIR; F42522; F42522.
DR   SMR; P21068; -.
DR   Proteomes; UP000008269; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IDA:UniProtKB.
DR   GO; GO:0042025; C:host cell nucleus; IDA:UniProtKB.
DR   GO; GO:0039644; P:suppression by virus of host NF-kappaB cascade; IDA:UniProtKB.
DR   InterPro; IPR009473; Orthopox_A49.
DR   Pfam; PF06489; Orthopox_A49R; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..162
FT                   /note="Protein A49"
FT                   /id="PRO_0000099342"
SQ   SEQUENCE   162 AA;  18753 MW;  EE91411C97509A75 CRC64;
     MDEAYYSGNL ESVLGYVSDM HTELASISQL VIAKIETIDN DILNKDIVNF IMCRSNLDNP
     FISFLDTVYT IIDQENYQTE LINSLDDNEI IDCIVNKFMS FYKDNLENIV DAIITLKYIM
     NNPDFKTTYA EVLGSRIADI DIKQVIRKNI LQLSNDIRER YL