ID   PERI_PERAI              Reviewed;          51 AA.
AC   P84117; P83551;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=Perinerin;
OS   Perinereis aibuhitensis (Clamworm) (Nereis aibuhitensis).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC   Errantia; Phyllodocida; Nereididae; Perinereis.
OX   NCBI_TaxID=126650;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, SYNTHESIS, FUNCTION, AND MASS SPECTROMETRY.
RX   PubMed=15113828; DOI=10.1093/jb/mvh036;
RA   Pan W.-D., Liu X.-H., Ge F., Han J., Zheng T.;
RT   "Perinerin, a novel antimicrobial peptide purified from the clamworm
RT   Perinereis aibuhitensis Grube and its partial characterization.";
RL   J. Biochem. 135:297-304(2004).
CC   -!- FUNCTION: Antibacterial activity against both Gram-negative and Gram-
CC       positive bacteria. Shows marked activity against P.aeruginosa,
CC       B.megaterium, A.viridans, moderate activity against E.coli K-12,
CC       S.aureus and M.luteus, and minor activity against P.vulgaris.
CC       Antifungal activity against P.heliothis. {ECO:0000269|PubMed:15113828}.
CC   -!- MASS SPECTROMETRY: Mass=5975; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:15113828};
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DR   AlphaFoldDB; P84117; -.
DR   SMR; P84117; -.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Fungicide.
FT   CHAIN           1..51
FT                   /note="Perinerin"
FT                   /id="PRO_0000058313"
SQ   SEQUENCE   51 AA;  5978 MW;  8D4ECA15B35EDDD2 CRC64;
     FNKLKQGSSK RTCAKCFRKI MPSVHELDER RRGANRWAAG FRKCVSSICR Y