ID   A49_VAR67               Reviewed;         162 AA.
AC   P0DSQ7; P33857;
DT   16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2019, sequence version 1.
DT   12-AUG-2020, entry version 5.
DE   RecName: Full=Protein A49;
GN   ORFNames=A49R, J3R;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1666548;
RA   Shchelkunov S.N., Marennikova S.S., Totmenin A.V., Blinov V.M.,
RA   Chizhikov V.E., Gutorov V.V., Safronov P.F., Pozdnyakov S.G.,
RA   Shelukhina E.M., Gashnikov P.V., Anjaparidze O.G., Sandakhchiev L.S.;
RT   "Creation of a clone library of fragments from the natural variola virus
RT   and study of the structural and functional organization of viral genes from
RT   a circle of hosts.";
RL   Dokl. Akad. Nauk SSSR 321:402-406(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
CC   -!- SIMILARITY: Belongs to the poxviridae A49 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X69198; CAA49102.1; -; Genomic_DNA.
DR   EMBL; X67118; CAA47544.1; -; Genomic_DNA.
DR   PIR; S46843; S46843.
DR   RefSeq; NP_042205.1; NC_001611.1.
DR   SMR; P0DSQ7; -.
DR   GeneID; 1486449; -.
DR   KEGG; vg:1486449; -.
DR   Proteomes; UP000002060; Genome.
DR   InterPro; IPR009473; Orthopox_A49.
DR   Pfam; PF06489; Orthopox_A49R; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..162
FT                   /note="Protein A49"
FT                   /id="PRO_0000099344"
SQ   SEQUENCE   162 AA;  18749 MW;  1883589730544714 CRC64;
     MDEGYYSGNL ESVLGYVSDM HTKLASITQL VIAKIETIDN DILNNDIVNF IMCRSNLNNP
     FISFLDTVYT IIDQEIYQNE LINSLDDNKI IDCIVNKFMS FYKDNLENIV DAIITLKYIM
     NNPDFKTTYA EVLGSRIADI DIKQVIRENI LQLSNDIRER YL