ID   PESC_PYRTR              Reviewed;         679 AA.
AC   B2WBA7;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 2.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Pescadillo homolog {ECO:0000255|HAMAP-Rule:MF_03028};
DE   AltName: Full=Nucleolar protein 7 homolog {ECO:0000255|HAMAP-Rule:MF_03028};
GN   Name=nop7; ORFNames=PTRG_06919;
OS   Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus)
OS   (Drechslera tritici-repentis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC   Pyrenophora.
OX   NCBI_TaxID=426418;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pt-1C-BFP;
RX   PubMed=23316438; DOI=10.1534/g3.112.004044;
RA   Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA   Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H.,
RA   Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W.,
RA   Schwartz D.C., Spatafora J.W., Turgeon B.G., Yandava C., Young S., Zhou S.,
RA   Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.;
RT   "Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-
RT   repentis, reveals transduplication and the impact of repeat elements on
RT   pathogenicity and population divergence.";
RL   G3 (Bethesda) 3:41-63(2013).
CC   -!- FUNCTION: Component of the NOP7 complex, which is required for
CC       maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S
CC       ribosome. {ECO:0000255|HAMAP-Rule:MF_03028}.
CC   -!- SUBUNIT: Component of the NOP7 complex, composed of erb1, nop7 and
CC       ytm1. The complex is held together by erb1, which interacts with nop7
CC       via its N-terminal domain and with ytm1 via a high-affinity interaction
CC       between the seven-bladed beta-propeller domains of the 2 proteins. The
CC       NOP7 complex associates with the 66S pre-ribosome. {ECO:0000255|HAMAP-
CC       Rule:MF_03028}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000255|HAMAP-
CC       Rule:MF_03028}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03028}.
CC   -!- SIMILARITY: Belongs to the pescadillo family. {ECO:0000255|HAMAP-
CC       Rule:MF_03028}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDU49839.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DS231621; EDU49839.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001937252.1; XM_001937217.1.
DR   AlphaFoldDB; B2WBA7; -.
DR   SMR; B2WBA7; -.
DR   STRING; 45151.EDU49839; -.
DR   GeneID; 6345188; -.
DR   eggNOG; KOG2481; Eukaryota.
DR   InParanoid; B2WBA7; -.
DR   OrthoDB; 777920at2759; -.
DR   Proteomes; UP000001471; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.10190; -; 1.
DR   HAMAP; MF_03028; Pescadillo; 1.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR010613; PES.
DR   PANTHER; PTHR12221; PTHR12221; 1.
DR   Pfam; PF06732; Pescadillo_N; 1.
DR   SUPFAM; SSF52113; SSF52113; 1.
DR   PROSITE; PS50172; BRCT; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..679
FT                   /note="Pescadillo homolog"
FT                   /id="PRO_0000370502"
FT   DOMAIN          351..471
FT                   /note="BRCT"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_03028"
FT   REGION          413..437
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          480..679
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          573..679
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_03028"
FT   COMPBIAS        504..528
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        540..577
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        578..679
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   679 AA;  75743 MW;  BA2D58AFA229D79F CRC64;
     MHILTPTQAP LVPNPPHELM YTSSPLQISL PDFRRLCIFK GIYPPREPRN KKKVSKGSTA
     ATTFYYTKDI QYLLHEPLLA KFREHKAVAK KIGRALGRGE SGDASRLEKN LMPKVKLDHI
     IKERYPTFVD ALRDLDDALS MLFLFANLPS SDHIPAKTIA LCQRLTREFE HYVITSHSLR
     KSFLSIKGIY YQATIQGQDI LWLVPYRFVQ RTGGDIDFRI MGTFVEFYTT LLGFVNYRLY
     TSIGLVYPPK FNARSDEQGG ELAAFQLEGK ATATNGASNG HAEDAEINPE AQAIADRIGA
     MPDVEEEEAT TAVAKTGAED DEEEANEEID KFEPTAPDAD ILPQPQASSA EVASLFAPFT
     FYLSRETPRG SLEFILKAFG CKRVGWDGVL GDGAFTTNES DPAITHQIVD RPALSNGAPA
     SNVQETENGG AAAPKAQWPY SMMPGRTYVQ PQWVWDSINQ GKLLRADHYS PGADLPPHLS
     PWVKPKKGEY DPNLPLAAQQ PEGEAEAFED EGDEETAFDV DGDEDMEAIV DREGSVEVGE
     GMDVADDSED DSDDDESDEE DGPAGDEDDL DSDAESDISE GEAARLQHQR ELEAEATGKK
     LEVKKPTRKE ENATIRKKAE KKKRAEEEER ERQKMMLSNK KRKLLKRIEY GENKRDNESE
     NLRRKRARVE KAKAAAEAV