PET8_ASHGO
ID PET8_ASHGO Reviewed; 271 AA.
AC O60029;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=Putative mitochondrial carrier protein PET8;
GN Name=PET8; OrderedLocusNames=AAL014C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RA Mohr C., Philippsen P.;
RT "Isolation of the Ashbya gossypii LEU2 gene and its use as a marker gene in
RT transformation experiments.";
RL Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000305};
CC Multi-pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; AJ006406; CAA07008.1; -; Genomic_DNA.
DR EMBL; AE016814; AAS50352.1; -; Genomic_DNA.
DR RefSeq; NP_982528.1; NM_207881.1.
DR AlphaFoldDB; O60029; -.
DR SMR; O60029; -.
DR STRING; 33169.AAS50352; -.
DR EnsemblFungi; AAS50352; AAS50352; AGOS_AAL014C.
DR GeneID; 4618508; -.
DR KEGG; ago:AGOS_AAL014C; -.
DR eggNOG; KOG0768; Eukaryota.
DR HOGENOM; CLU_015166_3_0_1; -.
DR InParanoid; O60029; -.
DR OMA; PRVGWIS; -.
DR Proteomes; UP000000591; Chromosome I.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0000095; F:S-adenosyl-L-methionine transmembrane transporter activity; IBA:GO_Central.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 4.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..271
FT /note="Putative mitochondrial carrier protein PET8"
FT /id="PRO_0000090685"
FT TRANSMEM 6..26
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 97..117
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 152..168
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 251..271
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 3..76
FT /note="Solcar 1"
FT REPEAT 91..177
FT /note="Solcar 2"
FT REPEAT 187..270
FT /note="Solcar 3"
SQ SEQUENCE 271 AA; 29870 MW; D92F3F45E97CC53F CRC64;
MDSTFLASLV SGAAAGTSTD VVFFPIDTLK TRLQAKGGFF HNGGYRGIYR GLGSAVVASA
PGASLFFVTY DSMKQQLRPV MGRWTASEQL AEVLTHMLSS SLGEMSACLV RVPAEVIKQR
TQTHHTNSSL QTLRLILRDP TGEGVVRGLY RGWWTTIMRE IPFTCIQFPL YEYLKKKWAA
YAEIERVSAW QGAVCGSLAG GIAAAATTPL DVLKTRMMLH ERRVPMLHLA RTLFREEGAR
VFFRGIGPRT MWISAGGAIF LGVYEAVHSL F