ID   PEX10_MACFA             Reviewed;         326 AA.
AC   Q8HXW8;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Peroxisome biogenesis factor 10;
DE   AltName: Full=Peroxin-10;
DE   AltName: Full=Peroxisomal biogenesis factor 10;
DE   AltName: Full=Peroxisome assembly protein 10;
GN   Name=PEX10; ORFNames=QccE-12251;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RA   Kusuda J., Osada N., Hida M., Sugano S., Hashimoto K.;
RT   "Isolation and characterization of cDNA for macaque neurological disease
RT   genes.";
RL   Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Somewhat implicated in the biogenesis of peroxisomes.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with PEX19. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000305}; Peripheral
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the pex2/pex10/pex12 family. {ECO:0000305}.
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DR   EMBL; AB083323; BAC20602.1; -; mRNA.
DR   RefSeq; NP_001270672.1; NM_001283743.1.
DR   AlphaFoldDB; Q8HXW8; -.
DR   STRING; 9541.XP_005545086.1; -.
DR   GeneID; 102145113; -.
DR   CTD; 5192; -.
DR   eggNOG; KOG0317; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0005779; C:integral component of peroxisomal membrane; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; ISS:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; ISS:UniProtKB.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR006845; Pex_N.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   Pfam; PF04757; Pex2_Pex12; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Metal-binding; Peroxisome; Peroxisome biogenesis;
KW   Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..326
FT                   /note="Peroxisome biogenesis factor 10"
FT                   /id="PRO_0000056377"
FT   ZN_FING         273..311
FT                   /note="RING-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
SQ   SEQUENCE   326 AA;  37132 MW;  E9D5C640D4F9DFDA CRC64;
     MAPAAASPPE VIRAAQKDEY YRGGLRSAAG GALHSLAGAR KWLEWRKEVE LLSDVAYFGL
     TTLAGYQTLG EEYVSIVRVD PSQTRVPSWL RRGVLVTLHA VLPYLLDKVL LPLEQELQAD
     PDSGRPSQGS LVPGGRGCSG VRRWVRRHTA TLTEQQRRAL LRAAFVLRQG LACLQQLHVA
     WFYIHGVFYH LAKRLTGITY LRVRSLPGED LRARVSYRLL GVVSLLHLVL SVGLRLYGFR
     QRQRARKEWR LHRGLSHRRG SLEERAVSRN PLCTLCLEER RHPTATPCGH LFCWECITAW
     CSSKAECPLC REKFPPQKLI YLRHYR