PEX11_SCHPO
ID PEX11_SCHPO Reviewed; 238 AA.
AC Q10333;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2001, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Peroxisomal biogenesis factor 11;
GN Name=pex11; ORFNames=SPBC582.09;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Involved in peroxisomal proliferation. Promotes peroxisome
CC division and biogenesis (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16823372}.
CC Peroxisome membrane {ECO:0000250}; Peripheral membrane protein
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the peroxin-11 family. {ECO:0000305}.
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DR EMBL; CU329671; CAB46672.1; -; Genomic_DNA.
DR PIR; T40568; T40568.
DR RefSeq; NP_595177.1; NM_001021085.2.
DR AlphaFoldDB; Q10333; -.
DR BioGRID; 277629; 18.
DR STRING; 4896.SPBC582.09.1; -.
DR iPTMnet; Q10333; -.
DR MaxQB; Q10333; -.
DR PaxDb; Q10333; -.
DR PRIDE; Q10333; -.
DR EnsemblFungi; SPBC582.09.1; SPBC582.09.1:pep; SPBC582.09.
DR GeneID; 2541114; -.
DR KEGG; spo:SPBC582.09; -.
DR PomBase; SPBC582.09; pex11.
DR VEuPathDB; FungiDB:SPBC582.09; -.
DR eggNOG; KOG4186; Eukaryota.
DR HOGENOM; CLU_049216_2_1_1; -.
DR InParanoid; Q10333; -.
DR OMA; VWNKNVH; -.
DR PhylomeDB; Q10333; -.
DR Reactome; R-SPO-9603798; Class I peroxisomal membrane protein import.
DR PRO; PR:Q10333; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005779; C:integral component of peroxisomal membrane; IEA:InterPro.
DR GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR GO; GO:0005778; C:peroxisomal membrane; IBA:GO_Central.
DR GO; GO:0019395; P:fatty acid oxidation; ISO:PomBase.
DR GO; GO:0016559; P:peroxisome fission; IBA:GO_Central.
DR GO; GO:0044375; P:regulation of peroxisome size; IBA:GO_Central.
DR InterPro; IPR008733; PEX11.
DR Pfam; PF05648; PEX11; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Peroxisome; Peroxisome biogenesis;
KW Reference proteome.
FT CHAIN 1..238
FT /note="Peroxisomal biogenesis factor 11"
FT /id="PRO_0000116518"
SQ SEQUENCE 238 AA; 26479 MW; 58095AA8CD708180 CRC64;
MAVIFENPQY VHVLRMLNSM PARDKTFRAL QFVAKLLSWH LFYGGSSLST VNKWKKLESN
ISFSRKLFSI GKVLDYICKV YFDSLKLQNP LSGNKSALPT ISFTKDVAFA GYATAELIGW
FNKTELMPCS HSKQISTIGK QCLAVALLSS CLAGCYELQQ NSKKIKSATQ EASEKDSTSL
QTLQKERKEI LFFALQNALD ATIPLAELDI LKVNDGFVAA AGITTSLMSV YKTWIGSY