ID   PEX13_BOVIN             Reviewed;         403 AA.
AC   Q0P5B1;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Peroxisomal membrane protein PEX13;
DE   AltName: Full=Peroxin-13;
GN   Name=PEX13;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal cerebellum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the peroxisomal translocation machinery with
CC       PEX14 and PEX17. Functions as a docking factor for the predominantly
CC       cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1
CC       and PTS2 proteins (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with PEX19. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peroxin-13 family. {ECO:0000305}.
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DR   EMBL; BC120277; AAI20278.1; -; mRNA.
DR   RefSeq; NP_001069680.1; NM_001076212.2.
DR   AlphaFoldDB; Q0P5B1; -.
DR   SMR; Q0P5B1; -.
DR   STRING; 9913.ENSBTAP00000006917; -.
DR   PaxDb; Q0P5B1; -.
DR   PRIDE; Q0P5B1; -.
DR   Ensembl; ENSBTAT00000006917; ENSBTAP00000006917; ENSBTAG00000005257.
DR   GeneID; 540337; -.
DR   KEGG; bta:540337; -.
DR   CTD; 5194; -.
DR   VEuPathDB; HostDB:ENSBTAG00000005257; -.
DR   VGNC; VGNC:32755; PEX13.
DR   eggNOG; KOG3875; Eukaryota.
DR   GeneTree; ENSGT00390000016883; -.
DR   HOGENOM; CLU_045457_0_0_1; -.
DR   InParanoid; Q0P5B1; -.
DR   OMA; QPKIRGW; -.
DR   OrthoDB; 1085263at2759; -.
DR   TreeFam; TF327117; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000005257; Expressed in spermatocyte and 106 other tissues.
DR   ExpressionAtlas; Q0P5B1; baseline.
DR   GO; GO:0005779; C:integral component of peroxisomal membrane; ISS:UniProtKB.
DR   GO; GO:1990429; C:peroxisomal importomer complex; IBA:GO_Central.
DR   GO; GO:0005778; C:peroxisomal membrane; ISS:UniProtKB.
DR   GO; GO:0021795; P:cerebral cortex cell migration; IEA:Ensembl.
DR   GO; GO:0001561; P:fatty acid alpha-oxidation; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0060152; P:microtubule-based peroxisome localization; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0016560; P:protein import into peroxisome matrix, docking; ISS:UniProtKB.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   InterPro; IPR007223; Peroxin-13_N.
DR   InterPro; IPR035463; Pex13.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR19332; PTHR19332; 1.
DR   Pfam; PF04088; Peroxin-13_N; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Peroxisome; Phosphoprotein; Protein transport;
KW   Reference proteome; SH3 domain; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..403
FT                   /note="Peroxisomal membrane protein PEX13"
FT                   /id="PRO_0000371413"
FT   TOPO_DOM        1..233
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        255..403
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          272..336
FT                   /note="SH3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT   REGION          1..69
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         354
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9D0K1"
SQ   SEQUENCE   403 AA;  44361 MW;  38F77CF4EA030A97 CRC64;
     MASQPPPPPK PWETRRIPGT GPGPGPGPTF QSAELGPTLL TRPGQPTLTR VPPPILPRPS
     QQTGSGNLNT FRPAYSSFSS GYGAYGNSFY GSYSPYSYGY NGLGYNRLRI DDLPPSRFVQ
     QAEESSRGAF QSIESIVHAF ASVSMMMDAT FSAVYNSFRA VLDVANHFSR LKIHFTKVFS
     AFALVRTIRY LYRRLQWMIG LRRGLENEDL WAESEGTVAC LGAEDRAANS AKSWPIFLFF
     AVILGGPYLI WKLLSTHSDE VTDSTNWASG EDDHVVARAE YDFVAVSEEE ISFRAGDMLN
     LALKEQQPRV RGWLLASLDG QTTGLIPANY VKILGKRRGR KTVESSRISK QQQSFTNTTL
     IKGATAADSL DDQEAAFESV FVETNKVPVA SDSTGKNGDK QDL