ID   PEX13_CAEEL             Reviewed;         330 AA.
AC   Q19951;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   06-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Probable peroxisomal membrane protein PEX13;
DE   AltName: Full=Peroxin-13;
GN   Name=prx-13; ORFNames=F32A5.6;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Component of the peroxisomal translocation machinery with
CC       PEX14 and PEX17. Functions as a docking factor for the predominantly
CC       cytoplasmic PTS1 receptor (PAS10/PEX5) (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peroxin-13 family. {ECO:0000305}.
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DR   EMBL; FO080735; CCD66278.1; -; Genomic_DNA.
DR   PIR; T16233; T16233.
DR   RefSeq; NP_495513.1; NM_063112.3.
DR   AlphaFoldDB; Q19951; -.
DR   SMR; Q19951; -.
DR   BioGRID; 39528; 31.
DR   IntAct; Q19951; 31.
DR   STRING; 6239.F32A5.6; -.
DR   EPD; Q19951; -.
DR   PaxDb; Q19951; -.
DR   PeptideAtlas; Q19951; -.
DR   EnsemblMetazoa; F32A5.6.1; F32A5.6.1; WBGene00004198.
DR   GeneID; 174192; -.
DR   KEGG; cel:CELE_F32A5.6; -.
DR   UCSC; F32A5.6; c. elegans.
DR   CTD; 174192; -.
DR   WormBase; F32A5.6; CE28290; WBGene00004198; prx-13.
DR   eggNOG; KOG3875; Eukaryota.
DR   GeneTree; ENSGT00390000016883; -.
DR   HOGENOM; CLU_045457_0_0_1; -.
DR   InParanoid; Q19951; -.
DR   OMA; QPKIRGW; -.
DR   OrthoDB; 1085263at2759; -.
DR   PhylomeDB; Q19951; -.
DR   Reactome; R-CEL-8866654; E3 ubiquitin ligases ubiquitinate target proteins.
DR   Reactome; R-CEL-9033241; Peroxisomal protein import.
DR   Reactome; R-CEL-9603798; Class I peroxisomal membrane protein import.
DR   SignaLink; Q19951; -.
DR   PRO; PR:Q19951; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00004198; Expressed in larva and 4 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:1990429; C:peroxisomal importomer complex; IBA:GO_Central.
DR   GO; GO:0005778; C:peroxisomal membrane; IBA:GO_Central.
DR   GO; GO:0002119; P:nematode larval development; IMP:WormBase.
DR   GO; GO:0016560; P:protein import into peroxisome matrix, docking; IBA:GO_Central.
DR   InterPro; IPR007223; Peroxin-13_N.
DR   InterPro; IPR035463; Pex13.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR19332; PTHR19332; 1.
DR   Pfam; PF04088; Peroxin-13_N; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Membrane; Peroxisome; Protein transport; Reference proteome; SH3 domain;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..330
FT                   /note="Probable peroxisomal membrane protein PEX13"
FT                   /id="PRO_0000058322"
FT   TOPO_DOM        1..192
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        214..330
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          235..300
FT                   /note="SH3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   330 AA;  35766 MW;  7DDD647F07A04403 CRC64;
     MSAPPTNQPP PLPPRSFDNQ MSNPMINTGF GYGGGYGMNT FPGSGMYGGG GMYGGGMGYG
     GFGGGFNHMG YGQGPDSNFA RLAEEQSRGA FQSIESVVNA VSSVANMLNS THNAVYSSFR
     AVIGVVEQFG RLKTQLSSVV VSLAVFRWVY RFWRWLLVML KLKPASYASA AEMAWGTSQP
     YATDVLGATR TPASVNWPAA LFWVVAIGGP WLIYRCVSQM VQAAEEKRKW ATGAAPHYTA
     QALFDFQASN EQELSFMNGE TLRVAPKEEQ PRVRGWLLAS VADGSRIGLV PINYVRIVGK
     QSQSPPLTQQ SNLDTFVNAF PARDLNSNIQ