ID   PEX13_SCHPO             Reviewed;         288 AA.
AC   O14136;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Peroxisomal membrane protein pex13;
DE   AltName: Full=Peroxin-13;
GN   Name=pex13; ORFNames=SPAC3C7.10;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Component of the peroxisomal translocation machinery with
CC       pex14 and pex17. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peroxin-13 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB16740.1; -; Genomic_DNA.
DR   PIR; T38696; T38696.
DR   RefSeq; NP_593611.1; NM_001019042.2.
DR   AlphaFoldDB; O14136; -.
DR   SMR; O14136; -.
DR   BioGRID; 279481; 22.
DR   STRING; 4896.SPAC3C7.10.1; -.
DR   MaxQB; O14136; -.
DR   PaxDb; O14136; -.
DR   PRIDE; O14136; -.
DR   EnsemblFungi; SPAC3C7.10.1; SPAC3C7.10.1:pep; SPAC3C7.10.
DR   GeneID; 2543046; -.
DR   KEGG; spo:SPAC3C7.10; -.
DR   PomBase; SPAC3C7.10; pex13.
DR   VEuPathDB; FungiDB:SPAC3C7.10; -.
DR   eggNOG; KOG3875; Eukaryota.
DR   HOGENOM; CLU_966951_0_0_1; -.
DR   InParanoid; O14136; -.
DR   OMA; LMAAHMS; -.
DR   PhylomeDB; O14136; -.
DR   Reactome; R-SPO-8866654; E3 ubiquitin ligases ubiquitinate target proteins.
DR   Reactome; R-SPO-9033241; Peroxisomal protein import.
DR   Reactome; R-SPO-9603798; Class I peroxisomal membrane protein import.
DR   PRO; PR:O14136; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:1990429; C:peroxisomal importomer complex; IBA:GO_Central.
DR   GO; GO:0005778; C:peroxisomal membrane; ISO:PomBase.
DR   GO; GO:0016560; P:protein import into peroxisome matrix, docking; IBA:GO_Central.
DR   InterPro; IPR007223; Peroxin-13_N.
DR   InterPro; IPR035463; Pex13.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR19332; PTHR19332; 1.
DR   Pfam; PF04088; Peroxin-13_N; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Membrane; Peroxisome; Reference proteome; SH3 domain; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..288
FT                   /note="Peroxisomal membrane protein pex13"
FT                   /id="PRO_0000310479"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          222..288
FT                   /note="SH3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..32
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   288 AA;  32055 MW;  992F93538CDE1E43 CRC64;
     METNQNEKGP SLPSYPAGGI MSVSNSNADT NQGVTQHPLA NRIVNPNYYN MGFNPYSGFN
     SFIPSFNPFV PLETNLPGNG PISSLQVIES IVGAVGSIAQ VLESTLMAAH MSYNTFVSVS
     ENLNKLKSSI GAIFGIVSLL SRLKRLVLKF FKHSKIDEMN SQEYDVFEKE EGNHKNSIYS
     IVSSLAIILG LVGLPYAIIR LFKNIYEKEK QIQQAKIRKK IDSLEFCKAD YEFMSRDPGV
     EMSLKKGDII AILSKTDTQG NPCEWWQGRK RSGETGWFPS NYCSIISR