ID   PEX16_DICDI             Reviewed;         400 AA.
AC   Q550G0; Q869V2;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Peroxisome biogenesis factor 16;
DE   AltName: Full=Peroxin-16;
GN   Name=pex16; ORFNames=DDB_G0277113;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Required for peroxisome membrane biogenesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peroxin-16 family. {ECO:0000305}.
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DR   EMBL; AAFI02000019; EAL69058.2; -; Genomic_DNA.
DR   RefSeq; XP_642972.2; XM_637880.2.
DR   AlphaFoldDB; Q550G0; -.
DR   STRING; 44689.DDB0238079; -.
DR   PaxDb; Q550G0; -.
DR   EnsemblProtists; EAL69058; EAL69058; DDB_G0277113.
DR   GeneID; 8620844; -.
DR   KEGG; ddi:DDB_G0277113; -.
DR   dictyBase; DDB_G0277113; pex16.
DR   eggNOG; KOG4546; Eukaryota.
DR   HOGENOM; CLU_036533_2_0_1; -.
DR   InParanoid; Q550G0; -.
DR   OMA; WGDKSSK; -.
DR   Reactome; R-DDI-9603798; Class I peroxisomal membrane protein import.
DR   PRO; PR:Q550G0; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005778; C:peroxisomal membrane; IBA:GO_Central.
DR   GO; GO:0005777; C:peroxisome; ISS:dictyBase.
DR   GO; GO:0007031; P:peroxisome organization; ISS:dictyBase.
DR   InterPro; IPR013919; Pex16.
DR   PANTHER; PTHR13299; PTHR13299; 1.
DR   Pfam; PF08610; Pex16; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Peroxisome biogenesis; Reference proteome.
FT   CHAIN           1..400
FT                   /note="Peroxisome biogenesis factor 16"
FT                   /id="PRO_0000371408"
FT   REGION          176..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   400 AA;  46981 MW;  D78CF312240FC88B CRC64;
     MIPKQPKSNI LIFLLENSDH LGLLKSLITF LPGRYGDSEL FSEGLYSVAN ILQSYLDYRS
     SGILLSNNID KISNGEKVPP PYYLTTLRWI TTVQSLELFF EMLATKKGEQ HDDSNSNNNN
     SNNNIKKMII FIIELLKAIL RLKLLIKTNG DMLVHHSFYV PSKDVKTILE NNRNQQKQFQ
     NKRPAVTMSI NNNNNINNND NNNINNNNNT NDDNFNNNNN NNNNRRTLSD QIFEQQRIVN
     QENNLLYQQQ RELQQNESTL IKLLPPPPPK DYNTKTIGEI LFIFRPVIYW VSYCIFGKKS
     WKPWFLSLVT ELLSKSFSEY GNFKQKIRLT LLEAKELNRR KKLLFFYLIR SPFYEKFIGD
     GLLNKFLNFL KKIHIFKTLI DILINYLNVY RTRYFYTSAS