ID   PEX17_YARLI             Reviewed;         671 AA.
AC   P87200; Q6CAQ1;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 2.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Peroxisomal membrane protein PEX17;
DE   AltName: Full=Peroxin-17;
GN   Name=PEX17; OrderedLocusNames=YALI0D00891g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=E 122;
RX   PubMed=9111320; DOI=10.1128/mcb.17.5.2511;
RA   Smith J.J., Szilard R.K., Marelli M., Rachubinski R.A.;
RT   "The peroxin Pex17p of the yeast Yarrowia lipolytica is associated
RT   peripherally with the peroxisomal membrane and is required for the import
RT   of a subset of matrix proteins.";
RL   Mol. Cell. Biol. 17:2511-2520(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in peroxisome biosynthesis. Required for the import
CC       of a subset of matrix proteins into peroxisomes.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane; Multi-pass membrane protein.
CC       Note=Probably associated with the matrix face of the membrane.
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DR   EMBL; U73028; AAC49693.1; -; Genomic_DNA.
DR   EMBL; CR382130; CAG80447.1; -; Genomic_DNA.
DR   RefSeq; XP_502261.1; XM_502261.1.
DR   AlphaFoldDB; P87200; -.
DR   EnsemblFungi; CAG80447; CAG80447; YALI0_D00891g.
DR   GeneID; 2910294; -.
DR   KEGG; yli:YALI0D00891g; -.
DR   VEuPathDB; FungiDB:YALI0_D00891g; -.
DR   HOGENOM; CLU_409510_0_0_1; -.
DR   InParanoid; P87200; -.
DR   OMA; VAIRWWY; -.
DR   Proteomes; UP000001300; Chromosome D.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Membrane; Peroxisome; Peroxisome biogenesis; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..671
FT                   /note="Peroxisomal membrane protein PEX17"
FT                   /id="PRO_0000058332"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        318..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        475..495
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        504..524
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        71..72
FT                   /note="LL -> PW (in Ref. 1; AAC49693)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   671 AA;  75532 MW;  0C7F92629542E9E6 CRC64;
     MNKYLVPPPQ ANRTVTNLDL LINNLRGSST PGAAEVDTRD ILQRIVFILP TIKNPLNLDL
     VIKEIINSPR LLPPLIDLHD YQQLTDAFRA TIKRKALVTD PTISFEAWLE TCFQVITRFA
     GPGWKKLPLL AGLILADYDI SADGPTLERK PGFPSKLKHL LKREFVTTFD QCLSIDTRNR
     SDATKWVPVL ACISIAQVYS LLGDVAINYR RFLQVGLDLI FSNYGLEMGT ALARLHAESG
     GDATTAGGLI GKKLKEPVVA LLNTFAHIAS SCIVHVDIDY IDRIQNKIIL VCENQAETWR
     ILTIESPTVM HHQESVQYLK WELFTLCIIM QGIANMLLTQ KMNQFMYLQL AYKQLQALHS
     IYFIVDQMGS QFAAYDYVFF SAIDVLLSEY APYIKNRGTI PPNKEFVAER LAANLAGTSN
     VGSHLPIDRS RVLFALNYYE QLVTVCHDSC VETIIYPMAR SFLYPTSDIQ QLKPLVEAAH
     SVILAGLAVP TNAVVNAKLI PEYMGGVLPL FPGVFSWNQF VLAIQSIVNT VSPPSEVFKT
     NQKLFRLVLD SLMKKCRDTP VGIPVPHSVT VSQEQEDIPP TQRAVVMLAL INSLPYVDIR
     SFELWLQETW NMIEATPMLA ENAPNKELAH AEHEFLVLEM WKMISGNIDQ RLNDVAIRWW
     YKKNARVHGT L