ID   PEX19_CAEEL             Reviewed;         282 AA.
AC   P34453;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Putative peroxisomal biogenesis factor 19;
DE   AltName: Full=Peroxin-19;
DE   Flags: Precursor;
GN   Name=prx-19; ORFNames=F54F2.8;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- INTERACTION:
CC       P34453; Q19766: tomm-20; NbExp=3; IntAct=EBI-320322, EBI-320312;
CC   -!- SUBCELLULAR LOCATION: Peroxisome {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peroxin-19 family. {ECO:0000305}.
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DR   EMBL; FO081385; CCD71242.1; -; Genomic_DNA.
DR   PIR; S44825; S44825.
DR   RefSeq; NP_498947.1; NM_066546.5.
DR   AlphaFoldDB; P34453; -.
DR   SMR; P34453; -.
DR   BioGRID; 41441; 4.
DR   DIP; DIP-25994N; -.
DR   IntAct; P34453; 2.
DR   STRING; 6239.F54F2.8.1; -.
DR   EPD; P34453; -.
DR   PaxDb; P34453; -.
DR   PeptideAtlas; P34453; -.
DR   EnsemblMetazoa; F54F2.8.1; F54F2.8.1; WBGene00004201.
DR   GeneID; 176239; -.
DR   KEGG; cel:CELE_F54F2.8; -.
DR   UCSC; F54F2.8.1; c. elegans.
DR   CTD; 176239; -.
DR   WormBase; F54F2.8; CE00201; WBGene00004201; prx-19.
DR   eggNOG; KOG3133; Eukaryota.
DR   GeneTree; ENSGT00390000010993; -.
DR   HOGENOM; CLU_043063_3_0_1; -.
DR   InParanoid; P34453; -.
DR   OMA; ASKEVMY; -.
DR   OrthoDB; 1282367at2759; -.
DR   PhylomeDB; P34453; -.
DR   Reactome; R-CEL-1369062; ABC transporters in lipid homeostasis.
DR   Reactome; R-CEL-9603798; Class I peroxisomal membrane protein import.
DR   PRO; PR:P34453; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00004201; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   GO; GO:0005778; C:peroxisomal membrane; IBA:GO_Central.
DR   GO; GO:0033328; F:peroxisome membrane targeting sequence binding; IBA:GO_Central.
DR   GO; GO:0002119; P:nematode larval development; IMP:WormBase.
DR   GO; GO:0045046; P:protein import into peroxisome membrane; IBA:GO_Central.
DR   Gene3D; 1.20.120.900; -; 1.
DR   InterPro; IPR006708; Pex19.
DR   InterPro; IPR038322; Pex19_C_sf.
DR   PANTHER; PTHR12774; PTHR12774; 1.
DR   Pfam; PF04614; Pex19; 1.
PE   1: Evidence at protein level;
KW   Lipoprotein; Methylation; Peroxisome; Prenylation; Reference proteome.
FT   CHAIN           1..279
FT                   /note="Putative peroxisomal biogenesis factor 19"
FT                   /id="PRO_0000218762"
FT   PROPEP          280..282
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000396704"
FT   REGION          73..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         279
FT                   /note="Cysteine methyl ester"
FT                   /evidence="ECO:0000255"
FT   LIPID           279
FT                   /note="S-farnesyl cysteine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   282 AA;  30988 MW;  681FBDF8FF08DBE4 CRC64;
     MTDETTQNIK DKTEEELAAL LDQTLGEFTA TPAPKPRTTD DELDELMASA DQEAAQKAAK
     DFQKMLEQMV TLQEEAMKKA GADPSEGEGE QPLDPNDPEA LAMMDALKQL MECSSNVANA
     SNPEEFMAGL DMLRSPNSPM EPFMSMIMQT LASKEVMYPP LKEIFDNYPK YLEDNGAGLD
     AETKERYEKQ FEVLGKICTE FEKQPELAEV QPVDAATQPA PEADPASIEH FEKLGKLLVE
     LQQYGYPPKE LVGALPDGWQ IDESGLPKVA DAAAATEACS IM