PEX19_DICDI
ID PEX19_DICDI Reviewed; 335 AA.
AC Q555I0;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Putative peroxisomal biogenesis factor 19;
DE AltName: Full=Peroxin-19;
GN Name=pex19; ORFNames=DDB_G0274873;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Peroxisome {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the peroxin-19 family. {ECO:0000305}.
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DR EMBL; AAFI02000012; EAL70329.1; -; Genomic_DNA.
DR RefSeq; XP_644089.1; XM_638997.1.
DR AlphaFoldDB; Q555I0; -.
DR SMR; Q555I0; -.
DR STRING; 44689.DDB0238080; -.
DR PaxDb; Q555I0; -.
DR EnsemblProtists; EAL70329; EAL70329; DDB_G0274873.
DR GeneID; 8619518; -.
DR KEGG; ddi:DDB_G0274873; -.
DR dictyBase; DDB_G0274873; pex19.
DR eggNOG; ENOG502RHD2; Eukaryota.
DR HOGENOM; CLU_830084_0_0_1; -.
DR InParanoid; Q555I0; -.
DR OMA; MGDSIND; -.
DR Reactome; R-DDI-1369062; ABC transporters in lipid homeostasis.
DR Reactome; R-DDI-9603798; Class I peroxisomal membrane protein import.
DR PRO; PR:Q555I0; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005778; C:peroxisomal membrane; ISS:dictyBase.
DR GO; GO:0033328; F:peroxisome membrane targeting sequence binding; IBA:GO_Central.
DR GO; GO:0045046; P:protein import into peroxisome membrane; IBA:GO_Central.
DR GO; GO:0006625; P:protein targeting to peroxisome; ISS:dictyBase.
DR Gene3D; 1.20.120.900; -; 1.
DR InterPro; IPR006708; Pex19.
DR InterPro; IPR038322; Pex19_C_sf.
DR PANTHER; PTHR12774; PTHR12774; 1.
DR Pfam; PF04614; Pex19; 1.
PE 3: Inferred from homology;
KW Peroxisome; Reference proteome.
FT CHAIN 1..335
FT /note="Putative peroxisomal biogenesis factor 19"
FT /id="PRO_0000356188"
FT REGION 14..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 335 AA; 37421 MW; 99371092CAA31CFC CRC64;
MNLDDLLNSA LDELETQEKE QPTTTKTTTT TTTTTTSNTT KTINNNNNTV TPSTIKPTYN
KPPPPSLGND DLLNTNVNDM MDIFKKLLGE ETLKNLDAGF DKEYNKDINN NSDDSNNGGL
PSEEDKKKID ELAEKLATMF GVSEDSDLGD MDNFKPFLEE LTKAGGLNFN NDELNNNSNN
NNKNNNNSGV HIDNFESSIS DTLKNLADNA SNKTDNNGGI DDLFSNLSKL MEGQNFNLDG
EETGQINDLF EESIQFMAEN YPDWIEKNID HYPPEETERF KNQSEIFSMI AQQKEGEADM
LDSGLLARMS QLGNLPDSFC EDSIKKVETE IDEKE