ID   PEX21_KLULA             Reviewed;         306 AA.
AC   Q6CN41;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Peroxisomal membrane protein PEX21;
DE   AltName: Full=Peroxin-21;
GN   Name=PEX21; OrderedLocusNames=KLLA0E15554g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in peroxisome biogenesis and the import of
CC       peroxisomal matrix proteins. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Peroxisome membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic
CC       side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peroxin-21 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99735.1; -; Genomic_DNA.
DR   RefSeq; XP_454648.1; XM_454648.1.
DR   AlphaFoldDB; Q6CN41; -.
DR   SMR; Q6CN41; -.
DR   STRING; 28985.XP_454648.1; -.
DR   EnsemblFungi; CAG99735; CAG99735; KLLA0_E15467g.
DR   GeneID; 2894705; -.
DR   KEGG; kla:KLLA0_E15467g; -.
DR   eggNOG; ENOG502S8JP; Eukaryota.
DR   HOGENOM; CLU_1054066_0_0_1; -.
DR   InParanoid; Q6CN41; -.
DR   OMA; NENSTIM; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cytoplasm; Membrane; Peroxisome; Reference proteome.
FT   CHAIN           1..306
FT                   /note="Peroxisomal membrane protein PEX21"
FT                   /id="PRO_0000301809"
FT   REGION          172..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   306 AA;  34075 MW;  BDFAC7DA58564AD7 CRC64;
     MSVCQTNPLN TLVSKSGYRF GQPNQHQQSI AQQQSRPRNN ALDHQFSQFT GASGPSFAHP
     QHQQLPMAAV VANATTAAST TSNTATASDH HVWIDQFANM QVHDKTEFPT DYKQMYSQYE
     ARGASYSMGA PVMVSHSQMF PRHQQSLMVN QLESQAYASS SAKLDEQFAE LERQVQDDEK
     EQQQDKDDDF HLKETSPLDE DQRQLKEAAQ SIYTTLSDKS STTSSKFSNS KFLGLMRNIS
     DGVITLKKNP DEDKYTELYS PSTGETFGEE YFPVQDSVLG DPLDSIGDLS NMSSSEAAAK
     VYHNSV