PEX22_ASHGO
ID PEX22_ASHGO Reviewed; 144 AA.
AC Q758W8;
DT 25-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Peroxisome assembly protein 22;
DE AltName: Full=Peroxin-22;
GN Name=PEX22; OrderedLocusNames=ADR410C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Involved in peroxisome biogenesis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000250}; Single-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the peroxin-22 family. {ECO:0000305}.
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DR EMBL; AE016817; AAS52329.1; -; Genomic_DNA.
DR RefSeq; NP_984505.1; NM_209858.1.
DR AlphaFoldDB; Q758W8; -.
DR SMR; Q758W8; -.
DR EnsemblFungi; AAS52329; AAS52329; AGOS_ADR410C.
DR GeneID; 4620670; -.
DR KEGG; ago:AGOS_ADR410C; -.
DR HOGENOM; CLU_121063_0_0_1; -.
DR InParanoid; Q758W8; -.
DR OMA; YKAINCE; -.
DR Proteomes; UP000000591; Chromosome IV.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.11730; -; 1.
DR InterPro; IPR024359; Peroxin-22.
DR InterPro; IPR038613; Peroxin-22_C_sf.
DR Pfam; PF12827; Peroxin-22; 1.
PE 3: Inferred from homology;
KW Membrane; Peroxisome; Peroxisome biogenesis; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..144
FT /note="Peroxisome assembly protein 22"
FT /id="PRO_0000058334"
FT TRANSMEM 13..35
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 144 AA; 15939 MW; E2DA813518F31B7A CRC64;
MVSKASRDQL RKYGAVSLAS LLVAASIVAY RWWNAAPSIE VEKKLRRSVS RCVVVTQGIQ
NEDMIHDLLF EDTVMLLAPG CTAEGRLKSA SRENAYKVIS CTTWQSVWAC VRHFRKHTLL
VRTSEVPSGV PADIGGYVSD ISDI